Synthesis of two benzamide-androgen derivatives

Lauro Figueroa-Valverde, Francisco Díaz-Cedillo, Elodia García-Cervera, Eduardo Pool-Gómez, Marcela Rosas-Nexticapa, Lenin Hau-Heredia, Betty Sarabia-Alcocer

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, two benzamide-androgen derivatives (N-(3-butyl-1-cyclohexyl-4-cyclohexylimino-azetidin-2-ylidene)-N′-[2-(17-hydroxy-10,13-dimethyl-hexadecahydro-cyclo penta[a]phenanthren-3-ylideneamino)ethyl]-4-(naphtalen-2-yloxy)benzamide and N-(3-butyl-1-cyclohexyl-4-cyclohexyliminoazetidin-2-ylidene)-N′-[2-(3-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-ylideneamino)ethyl]-4-(naphtalen-2-yloxy)benzamide were synthesized using some strategies. The structure of the compounds was confirmed by elemental analysis, spectroscopy and spectrometry data. The proposed method offers some advantages such as simple procedure, low cost and ease of workup.

Original languageEnglish
Pages (from-to)1781-1785
Number of pages5
JournalAsian Journal of Chemistry
Volume27
Issue number5
DOIs
StatePublished - 2015

Keywords

  • Boric acid.
  • Dihydrotestosterone androsterone

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