Synthesis of new succinate-dihydrotestosterone-dihydropyrimidine conjugate

L. Figueroa-Valverde, F. Díaz-Cedillo, A. Camacho-Luis

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A new steroid-dihydropyrimidine derivative has been synthesized. The route involves preparation of dihydrotestosterone-dihydropyrimidine derivative 4 using dihydrotestosterone 1, benzaldheyde 2, and thiourea 3 in presence of hydrochloric acid, followed by esterification of 4 with succinic acid 5 which results in the formation of succinatedihydrotestosterone-dihydropyrimidine conjugate 6.

Original languageEnglish
Pages (from-to)1757-1760
Number of pages4
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Volume48
Issue number12
StatePublished - Dec 2009
Externally publishedYes

Keywords

  • Dihydropyrimidine
  • Dihydrotestosterone
  • Steroid
  • Succinate
  • Succinic acid

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