TY - GEN
T1 - Synthesis of HAp/chitosan composites via electrospinning
T2 - 2008 5th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2008
AU - Vázquez-Hernández, F.
AU - Lopez-Haro, S. A.
AU - Lira, M. A.Meléndez
AU - De Lourdes Albor-Aguilera, María
AU - Altuzar, V.
AU - Mendoza-Barrera, C.
PY - 2008
Y1 - 2008
N2 - Human bone is a hydroxyapatite HAp (HCa5O13P 3) and type I collagen based composite. Nowadays, many methods and techniques have been developed and applied to design advanced materials for bone replacement. A strategy for imitating in a tridimensional way the structure, composition and mechanical properties of a bone is mimicking it at nanometric scale. This can be carried out, by incorporating selective of nanoparticles of apatites into a polymeric matrix by controlling structure and composition of the fibers. In this work we present the preliminary results of HAp/Chitosan composites prepared by the electrospinning technique. HAp/Chitosan fibers were spun from different aqueous solutions, all of them with a pH= 3. The compositional and structural characteristics were obtained by using scanning electron microscopy SEM, energy dispersive spectroscopy EDS, X-ray diffraction XRD, and infrared spectroscopy IRS. EDS and XRD confirmed that the mineral deposits correspond to hydroxyapatite and calcium phosphate monobasic MCP (CaH4O8P2)) which are present in the human bones. Comparative studies were made from chitosan and HAp/Chitosan solutions. In this respect IRS analysis showed that the characteristic chitosan stretch band in the 1020-1220 cm-1 range was attenuated when HAp was added. Additionally, from a precursor solution prepared at pH=3, 1% w/v chitosan, and 1% w/v HAp and spun at 20 V, a Ca/P ratio close to bone composition (Ca/P bone = 1.67) was obtained.
AB - Human bone is a hydroxyapatite HAp (HCa5O13P 3) and type I collagen based composite. Nowadays, many methods and techniques have been developed and applied to design advanced materials for bone replacement. A strategy for imitating in a tridimensional way the structure, composition and mechanical properties of a bone is mimicking it at nanometric scale. This can be carried out, by incorporating selective of nanoparticles of apatites into a polymeric matrix by controlling structure and composition of the fibers. In this work we present the preliminary results of HAp/Chitosan composites prepared by the electrospinning technique. HAp/Chitosan fibers were spun from different aqueous solutions, all of them with a pH= 3. The compositional and structural characteristics were obtained by using scanning electron microscopy SEM, energy dispersive spectroscopy EDS, X-ray diffraction XRD, and infrared spectroscopy IRS. EDS and XRD confirmed that the mineral deposits correspond to hydroxyapatite and calcium phosphate monobasic MCP (CaH4O8P2)) which are present in the human bones. Comparative studies were made from chitosan and HAp/Chitosan solutions. In this respect IRS analysis showed that the characteristic chitosan stretch band in the 1020-1220 cm-1 range was attenuated when HAp was added. Additionally, from a precursor solution prepared at pH=3, 1% w/v chitosan, and 1% w/v HAp and spun at 20 V, a Ca/P ratio close to bone composition (Ca/P bone = 1.67) was obtained.
KW - Bone
KW - Chitosan
KW - Composite
KW - Hydroxyapatite
UR - http://www.scopus.com/inward/record.url?scp=61549102108&partnerID=8YFLogxK
U2 - 10.1109/ICEEE.2008.4723410
DO - 10.1109/ICEEE.2008.4723410
M3 - Contribución a la conferencia
AN - SCOPUS:61549102108
SN - 9781424424993
T3 - 2008 5th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2008
SP - 238
EP - 241
BT - 2008 5th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2008
Y2 - 12 November 2008 through 14 November 2008
ER -