TY - JOUR
T1 - Synthesis of a progesterone-carbachol derivative
T2 - Relationship with some parameters involved in its geometry and electronic structure
AU - Figueroa-Valverde, Lauro
AU - Díaz-Cedillo, Francisco
AU - López-Ramos, María
AU - García-Cervera, Elodia
AU - Pool-Gomez, Eduardo
PY - 2012
Y1 - 2012
N2 - In this study, a progesterone-carbachol (3) derivative was synthetized and its relationship with some physicochemical parameters involved in its geometry and electronic structure wasevaluated. The results showed an increase in the HOMO/LUMO, logP and p values of compound 3 with respect to progesterone. All this datasuggest that changes in the chemical structure of progesterone to form progesteronecarbacholexert variations in HOMO/LUMO, log P and π values.
AB - In this study, a progesterone-carbachol (3) derivative was synthetized and its relationship with some physicochemical parameters involved in its geometry and electronic structure wasevaluated. The results showed an increase in the HOMO/LUMO, logP and p values of compound 3 with respect to progesterone. All this datasuggest that changes in the chemical structure of progesterone to form progesteronecarbacholexert variations in HOMO/LUMO, log P and π values.
KW - Carbachol
KW - Log P
KW - Physicochemical parameters
KW - Progesterone
UR - http://www.scopus.com/inward/record.url?scp=84861623278&partnerID=8YFLogxK
M3 - Artículo
SN - 0970-7077
VL - 24
SP - 2013
EP - 2016
JO - Asian Journal of Chemistry
JF - Asian Journal of Chemistry
IS - 5
ER -