Synthesis of 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone

Roberto Martínez; Georgina Espinosa-Pérez; Marco Brito-Arias

doi:10.1007/BF01666107

Synthesis of 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone

Roberto Martínez, Georgina Espinosa-Pérez, Marco Brito-Arias

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5 Scopus citations

Abstract

The acridinone derivative 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone (4) has been prepared in a two step fashion and the molecular structure confirmed by X-ray diffraction. Compound 4 crystallizes in the space group P2_l/n with a=6.022(2), b=21.111(2), c=9.604(2) Å, β=99.97(2)°, and Z=4. The single crystal analysis showed the acridinone tricyclic ring is virtually planar except in the gem-dimethyl position of C(3) which presented a half-chair conformation.

Original language	English
Pages (from-to)	201-203
Number of pages	3
Journal	Journal of Chemical Crystallography
Volume	25
Issue number	4
DOIs	https://doi.org/10.1007/BF01666107
State	Published - Apr 1995
Externally published	Yes

Keywords

Acridinone
alzheimer
dimedone

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10.1007/BF01666107

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@article{baa3d48c338b4d06b9cef73ba44d1a88,

title = "Synthesis of 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone",

abstract = "The acridinone derivative 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone (4) has been prepared in a two step fashion and the molecular structure confirmed by X-ray diffraction. Compound 4 crystallizes in the space group P2l/n with a=6.022(2), b=21.111(2), c=9.604(2) {\AA}, β=99.97(2)°, and Z=4. The single crystal analysis showed the acridinone tricyclic ring is virtually planar except in the gem-dimethyl position of C(3) which presented a half-chair conformation.",

keywords = "Acridinone, alzheimer, dimedone",

author = "Roberto Mart{\'i}nez and Georgina Espinosa-P{\'e}rez and Marco Brito-Arias",

year = "1995",

month = apr,

doi = "10.1007/BF01666107",

language = "Ingl{\'e}s",

volume = "25",

pages = "201--203",

journal = "Journal of Chemical Crystallography",

issn = "1074-1542",

number = "4",

}

TY - JOUR

T1 - Synthesis of 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone

AU - Martínez, Roberto

AU - Espinosa-Pérez, Georgina

AU - Brito-Arias, Marco

PY - 1995/4

Y1 - 1995/4

N2 - The acridinone derivative 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone (4) has been prepared in a two step fashion and the molecular structure confirmed by X-ray diffraction. Compound 4 crystallizes in the space group P2l/n with a=6.022(2), b=21.111(2), c=9.604(2) Å, β=99.97(2)°, and Z=4. The single crystal analysis showed the acridinone tricyclic ring is virtually planar except in the gem-dimethyl position of C(3) which presented a half-chair conformation.

AB - The acridinone derivative 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone (4) has been prepared in a two step fashion and the molecular structure confirmed by X-ray diffraction. Compound 4 crystallizes in the space group P2l/n with a=6.022(2), b=21.111(2), c=9.604(2) Å, β=99.97(2)°, and Z=4. The single crystal analysis showed the acridinone tricyclic ring is virtually planar except in the gem-dimethyl position of C(3) which presented a half-chair conformation.

KW - Acridinone

KW - alzheimer

KW - dimedone

UR - http://www.scopus.com/inward/record.url?scp=21844525074&partnerID=8YFLogxK

U2 - 10.1007/BF01666107

DO - 10.1007/BF01666107

M3 - Artículo

SN - 1074-1542

VL - 25

SP - 201

EP - 203

JO - Journal of Chemical Crystallography

JF - Journal of Chemical Crystallography

IS - 4

ER -

Synthesis of 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone

Abstract

Keywords

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