Synthesis and biological activities of organotin(Iv) complexes as antitumoral and antimicrobial agents. A review

Syed Shoaib Ahmad Shah; Muhammad Ashfaq; Amir Waseem; M. Mehboob Ahmed; Tayyaba Najam; Salma Shaheen; Gildardo Rivera

doi:10.2174/138955751505150408142958

Synthesis and biological activities of organotin(Iv) complexes as antitumoral and antimicrobial agents. A review

Syed Shoaib Ahmad Shah, Muhammad Ashfaq, Amir Waseem, M. Mehboob Ahmed, Tayyaba Najam, Salma Shaheen, Gildardo Rivera

Centro de Biotecnología Genómica (CBG)

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Advances in the use of organotin(IV) compounds have gained relevant interest in both the chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug development as biologically active agents, and in other areas. This review focuses on recent progress in the classical and convenient synthesis procedure, on their mechanism of action, and biological activities as antitumoral and antimicrobial agents.

Original language	English
Pages (from-to)	406-426
Number of pages	21
Journal	Mini-Reviews in Medicinal Chemistry
Volume	15
Issue number	5
DOIs	https://doi.org/10.2174/138955751505150408142958
State	Published - 1 Jan 2015

Keywords

Agents
Antimicrobial
Antitumoral
Organotin(IV)
Synthesis

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abstract = "Advances in the use of organotin(IV) compounds have gained relevant interest in both the chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug development as biologically active agents, and in other areas. This review focuses on recent progress in the classical and convenient synthesis procedure, on their mechanism of action, and biological activities as antitumoral and antimicrobial agents.",

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AU - Ahmad Shah, Syed Shoaib

AU - Ashfaq, Muhammad

AU - Waseem, Amir

AU - Ahmed, M. Mehboob

AU - Najam, Tayyaba

AU - Shaheen, Salma

AU - Rivera, Gildardo

PY - 2015/1/1

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N2 - Advances in the use of organotin(IV) compounds have gained relevant interest in both the chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug development as biologically active agents, and in other areas. This review focuses on recent progress in the classical and convenient synthesis procedure, on their mechanism of action, and biological activities as antitumoral and antimicrobial agents.

AB - Advances in the use of organotin(IV) compounds have gained relevant interest in both the chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug development as biologically active agents, and in other areas. This review focuses on recent progress in the classical and convenient synthesis procedure, on their mechanism of action, and biological activities as antitumoral and antimicrobial agents.

KW - Agents

KW - Antimicrobial

KW - Antitumoral

KW - Organotin(IV)

KW - Synthesis

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DO - 10.2174/138955751505150408142958

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JO - Mini-Reviews in Medicinal Chemistry

JF - Mini-Reviews in Medicinal Chemistry

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ER -

Synthesis and biological activities of organotin(Iv) complexes as antitumoral and antimicrobial agents. A review

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Keywords

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