TY - JOUR
T1 - 35Cl profiling using centric scan SPRITE with variable flip angle excitation
AU - Romanenko, Konstantin V.
AU - Cano-Barrita, P. F.de J.
AU - Balcom, Bruce J.
N1 - Funding Information:
The UNB MRI Centre is supported by an NSERC Major Resources Support Award. BJB acknowledges NSERC for Discovery and Equipment Grants and the Canada Chairs program for a Research Chair in MRI of Materials. P.F. de J. Cano acknowledges the support from the Instituto Politecnico Nacional de Mexico for the sabbatical year 2007–2008, and CONACYT from Mexico for a sabbatical scholarship.
PY - 2009/5
Y1 - 2009/5
N2 - An efficient MRI technique for quantitative density profiling of samples with fast spin-lattice relaxation (T1 < 5 ms) is introduced. The pulse scheme is based on the 1D centric scan SPRITE technique. Strong excitation of the sample at the k-space origin improves the sensitivity with respect to the original centric scan SPRITE technique. Radio frequency pulse durations are defined so as to provide uniform excitation of the sample at every k-space point. For a particular k-space point the pulse duration is required to be less than the inverse sample bandwidth. Simulations permit one to examine distortions from ideal profile geometry due to flip angle and spin-lattice relaxation effects. The proposed technique is especially suitable for the observation of low sensitivity samples, in particular, low-γ nuclei like 35Cl. In some cases, this strategy permits one to reduce the number of scans, i.e. the experiment time, by a factor of 100, depending on hardware, sample length and tolerable resolution loss. The designed pulse scheme is tested on cylindrical agar gel and type 1 Portland cement paste phantoms prepared to provide 1H and 35Cl signals, respectively.
AB - An efficient MRI technique for quantitative density profiling of samples with fast spin-lattice relaxation (T1 < 5 ms) is introduced. The pulse scheme is based on the 1D centric scan SPRITE technique. Strong excitation of the sample at the k-space origin improves the sensitivity with respect to the original centric scan SPRITE technique. Radio frequency pulse durations are defined so as to provide uniform excitation of the sample at every k-space point. For a particular k-space point the pulse duration is required to be less than the inverse sample bandwidth. Simulations permit one to examine distortions from ideal profile geometry due to flip angle and spin-lattice relaxation effects. The proposed technique is especially suitable for the observation of low sensitivity samples, in particular, low-γ nuclei like 35Cl. In some cases, this strategy permits one to reduce the number of scans, i.e. the experiment time, by a factor of 100, depending on hardware, sample length and tolerable resolution loss. The designed pulse scheme is tested on cylindrical agar gel and type 1 Portland cement paste phantoms prepared to provide 1H and 35Cl signals, respectively.
KW - Centric scan
KW - Cl MRI
KW - Non-proton
KW - Portland cement
KW - Relaxation time
KW - SPRITE
UR - http://www.scopus.com/inward/record.url?scp=63549101283&partnerID=8YFLogxK
U2 - 10.1016/j.jmr.2009.01.007
DO - 10.1016/j.jmr.2009.01.007
M3 - Artículo
C2 - 19201634
SN - 1090-7807
VL - 198
SP - 24
EP - 30
JO - Journal of Magnetic Resonance
JF - Journal of Magnetic Resonance
IS - 1
ER -