TY - JOUR
T1 - Structural features of 1-furoylthioureas 3-monosubstituted and 3,3-disubstituted
T2 - Coordination to cadmium and analytical applications
AU - Estévez-Hernández, O.
AU - Duque, J.
AU - Reguera, E.
PY - 2011/6
Y1 - 2011/6
N2 - The structural features of two series of 1-furoylthioureas 3-monosubstituted (Series 1) and 3,3-disubstituted (Series 2) 1-furoylthioureas and their CdCl2 complexes are discussed. The coordination strength through the sulfur atom is determined by the ligand structure. In Series 1 ligands, the carbonyl group and the proton on N2 are engaged in a strong hydrogen bond interaction. This leads to an S-shaped conformation type of the C=O and C=S groups where these donor sites reach a maximum separation. In the absence of that hydrogen bridge in 3,3-disubstituted derivatives, the C=O and C=S groups can adopt a U-shaped conformation type. This feature is also observed for two novel crystal structures of 1-(2-furoyl)-3-(2-hydroxyethyl)thiourea and 1-furoyl-3-ethyl-3-phenylthiourea, as determined by X-ray diffractometry and reported here. Emphasis is placed on the relationship between structural features of these ligands and their behavior as cadmium ionophores in potentiometric and amperometric sensors.
AB - The structural features of two series of 1-furoylthioureas 3-monosubstituted (Series 1) and 3,3-disubstituted (Series 2) 1-furoylthioureas and their CdCl2 complexes are discussed. The coordination strength through the sulfur atom is determined by the ligand structure. In Series 1 ligands, the carbonyl group and the proton on N2 are engaged in a strong hydrogen bond interaction. This leads to an S-shaped conformation type of the C=O and C=S groups where these donor sites reach a maximum separation. In the absence of that hydrogen bridge in 3,3-disubstituted derivatives, the C=O and C=S groups can adopt a U-shaped conformation type. This feature is also observed for two novel crystal structures of 1-(2-furoyl)-3-(2-hydroxyethyl)thiourea and 1-furoyl-3-ethyl-3-phenylthiourea, as determined by X-ray diffractometry and reported here. Emphasis is placed on the relationship between structural features of these ligands and their behavior as cadmium ionophores in potentiometric and amperometric sensors.
KW - Cd(II) complexes
KW - Raman
KW - crystal structure
KW - furoylthioureas
KW - ionophores
UR - http://www.scopus.com/inward/record.url?scp=79957617147&partnerID=8YFLogxK
U2 - 10.1080/17415993.2011.566926
DO - 10.1080/17415993.2011.566926
M3 - Artículo
SN - 1741-5993
VL - 32
SP - 213
EP - 222
JO - Journal of Sulfur Chemistry
JF - Journal of Sulfur Chemistry
IS - 3
ER -