TY - JOUR
T1 - Spray Drying Conditions of Antioxidant and Anti-inflammatory Polyphenols in Microcapsules of Ultrasound Assisted Extract of Salvilla (Buddleja scordioides Kunth)
AU - Maciás-Cortés, Elizabeth
AU - Gallegos-Infante, José Alberto
AU - Rocha-Guzmán, Nuria Elizabeth
AU - Moreno-Jiménez, Martha Roció
AU - Villanueva-Fierro, Ignacio
AU - Ochoa-Martínez, Luz Araceli
AU - Candelas-Cadillo, Mariá Guadalupe
AU - Rosas-Flores, Walfred
AU - Medina-Torres, Luis
AU - Rodríguez-Herrera, Raúl
AU - González-Laredo, Rubén Francisco
N1 - Funding Information:
E.M.-C. thanks Mexican Council of Science and Technology (CONACYT) for PhD scholarship.
Funding Information:
Partial financial support is acknowledged from TecNM-SEP, Mexican Ministry of Education (Grant No. 14506.22-P).
Publisher Copyright:
© 2022 The authors.
PY - 2022
Y1 - 2022
N2 - The consumption of natural products against gastrointestinal disorders has been increasing. Although there are pharmaceutical treatments, they present side effects, so new alternatives like nutraceuticals are investigated. Salvilla is used as a traditional treatment due to its bioactive phenolic content. Such extracts may be obtained by ultrasound assisted extraction (UAE) and microencapsulated to preserve them and develop a nutraceutical product. Therefore, salvilla extract was obtained by UAE and microencapsulation by spray drying (SD). Treatments were tested for yield, moisture, antioxidant activity, quantification of phenolic compounds, flow analysis, spectrometry by Raman and FTIR-ATR, extract release, and COX-2 inhibition. All treatments presented high antioxidant activity (74.8-93.4%). UPLC analysis showed a higher concentration of flavonoids than phenolic acids. Microencapsulation was confirmed, showing an inhibition of 55% of COX-2. Treatment SD8/160 showed a good protection of compounds and COX-2 inhibition. Thus, SD technology is a good option in the formulation of salvilla nutraceuticals.
AB - The consumption of natural products against gastrointestinal disorders has been increasing. Although there are pharmaceutical treatments, they present side effects, so new alternatives like nutraceuticals are investigated. Salvilla is used as a traditional treatment due to its bioactive phenolic content. Such extracts may be obtained by ultrasound assisted extraction (UAE) and microencapsulated to preserve them and develop a nutraceutical product. Therefore, salvilla extract was obtained by UAE and microencapsulation by spray drying (SD). Treatments were tested for yield, moisture, antioxidant activity, quantification of phenolic compounds, flow analysis, spectrometry by Raman and FTIR-ATR, extract release, and COX-2 inhibition. All treatments presented high antioxidant activity (74.8-93.4%). UPLC analysis showed a higher concentration of flavonoids than phenolic acids. Microencapsulation was confirmed, showing an inhibition of 55% of COX-2. Treatment SD8/160 showed a good protection of compounds and COX-2 inhibition. Thus, SD technology is a good option in the formulation of salvilla nutraceuticals.
KW - COX-2
KW - microencapsulation
KW - phenolic compounds
KW - salvilla
KW - spray drying
UR - http://www.scopus.com/inward/record.url?scp=85139458864&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/f8711afa-6a37-3d14-bd5c-ec15d9deb56a/
U2 - 10.1021/acsfoodscitech.2c00212
DO - 10.1021/acsfoodscitech.2c00212
M3 - Artículo
AN - SCOPUS:85139458864
SN - 2692-1944
VL - 2
SP - 1574
EP - 1585
JO - ACS Food Science and Technology
JF - ACS Food Science and Technology
IS - 10
ER -