Short report: Experimental infections of Oryzomys couesi with sympatric arboviruses from Mexico

Eleanor R. Deardorff, Naomi L. Forrester, Amelia P. Travassos Da Rosa, Jose G. Estrada-Franco, Roberto Navarro-Lopez, Robert B. Tesh, Scott C. Weaver

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Coues rice rat (Oryzomys couesi), a species abundant throughout Central America, was evaluated experimentally for the ability to serve as an amplifying host for three arboviruses: Patois (Bunyaviridae, Orthobunyavirus), Nepuyo (Orthobunyavirus), and Venezuelan equine encephalitis virus subtype ID (Togaviridae, Alphavirus).These three viruses have similar ecologies and are known to co-circulate in nature. Animals from all three cohorts survived infection and developed viremia with no apparent signs of illness and long-lasting antibodies. Thus, O. couesi may play a role in the general maintenance of these viruses in nature.

Original languageEnglish
Pages (from-to)350-353
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume82
Issue number2
DOIs
StatePublished - Feb 2010
Externally publishedYes

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