TY - GEN
T1 - Robust control for propofol induced anesthesia based on second-order sliding-mode control
AU - Hernández, Ana Gabriela Gallardo
AU - Fridman, Leonid
AU - Escobar, Aldo Eslava
AU - Davila, Jorge
AU - Leder, Ron
AU - Monsalve, Cristina Revilla
AU - Andrade, Sergio Islas
AU - Hernández, Ana Luisa
PY - 2013
Y1 - 2013
N2 - The effect of anesthesia can be different in every patient. It is often the case that anesthesia has to be induced in emergency situations, where identification of the patient's parameters cannot be done. It is preferable to have a controller insensitive to parameter variations, such as Second-Order Sliding-ModeControl (SOSMC). This kind of controller is also robust with respect to singular perturbations that may occur during surgery; therefore SOSMC is well suited to perform a closed loop propofol dosage. This in silico study tests the performance of an SOSMC for 4 different patients, to evaluate its insensibility to parameter variation (interpatient variability). SOSMC robustness with respect to perturbations is evaluated by a bleeding simulation, that changes the parameters of the pharmacokinetic model (intrapatient variability), and also by inducing a surgical stimuli.
AB - The effect of anesthesia can be different in every patient. It is often the case that anesthesia has to be induced in emergency situations, where identification of the patient's parameters cannot be done. It is preferable to have a controller insensitive to parameter variations, such as Second-Order Sliding-ModeControl (SOSMC). This kind of controller is also robust with respect to singular perturbations that may occur during surgery; therefore SOSMC is well suited to perform a closed loop propofol dosage. This in silico study tests the performance of an SOSMC for 4 different patients, to evaluate its insensibility to parameter variation (interpatient variability). SOSMC robustness with respect to perturbations is evaluated by a bleeding simulation, that changes the parameters of the pharmacokinetic model (intrapatient variability), and also by inducing a surgical stimuli.
UR - http://www.scopus.com/inward/record.url?scp=84902313446&partnerID=8YFLogxK
U2 - 10.1109/CDC.2013.6760318
DO - 10.1109/CDC.2013.6760318
M3 - Contribución a la conferencia
AN - SCOPUS:84902313446
SN - 9781467357173
T3 - Proceedings of the IEEE Conference on Decision and Control
SP - 2864
EP - 2869
BT - 2013 IEEE 52nd Annual Conference on Decision and Control, CDC 2013
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 52nd IEEE Conference on Decision and Control, CDC 2013
Y2 - 10 December 2013 through 13 December 2013
ER -