Abstract
We report that a toxin neutralization assay (TNA) can detect a decrease in the immunogenicity of anthrax vaccines as a consequence of brief exposure to elevated temperature. This attribute of TNA may help in adopting immunogenicity as a replacement of the current potency test, which involves protection from lethal challenge.
Original language | English |
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Pages (from-to) | 349-351 |
Number of pages | 3 |
Journal | Clinical and Vaccine Immunology |
Volume | 18 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2011 |