Psychological, immunological, and endocrinological implications of atopic dermatitis

Claudia Beltrán de Paz, Graciela Flores Sandoval, Modesto Orea Solano, Javier Gómez Vera, Ernestina Serrano Miranda, Patricia Sevilla Flores, Yurhixy Juárez Rojas, Sergio Estrada Parra

Research output: Contribution to journalArticle


BACKGROUND: The atopic dermatitis is a chronic disease with immunological alterations, neuro-immune-endocrine implications and repercussions in the psyche. OBJECTIVE: To determine the effectiveness of the use of psychological support in the treatment of atopic dermatitis. MATERIAL AND METHODS: This study included 20 patients (from 15 to 50 years old) with moderated and severe atopic dermatitis based on the Hanifin and Rafka modified criteria. They were classified in three groups of treatment: A) 10 patients with transfer factor and psychological support, B) 10 with transference factor without psychological support, C) 10 healthy individuals as a control group. At the beginning and ending of the analysis the degree of severity of the illness was determined using the SCORAD scale. RESULTS: There was a more statistically significant clinical improvement on group A than in group B, besides a decrease in anxiety and depression, at a laboratory level including hormonal behavior, without meaningful changes. CONCLUSIONS: It was demonstrated that the treatment with immune-modulator and psychological support on the moderated and severe atopic dermatitis improves the clinical and immunological evolution of this illness.
Original languageAmerican English
Pages (from-to)54-59
Number of pages6
JournalRevista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
StatePublished - 1 Jan 2003
Externally publishedYes


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