TY - JOUR
T1 - Presence of rare hepatitis C virus subtypes, 2j, 2k, and 2r in Mexico City as identified by sequencing
AU - Uribe-Noguez, Luis Antonio
AU - Ocaña-Mondragón, Alicia
AU - Mata-Marín, José Antonio
AU - Gómez-Torres, María Elena
AU - Ribas-Aparicio, Rosa María
AU - de la Luz Martínez-Rodríguez, María
N1 - Publisher Copyright:
© 2018 Wiley Periodicals, Inc.
PY - 2018/7
Y1 - 2018/7
N2 - The HCV 5'UTR, Core/E1, and NS5B regions of samples from fifty patients infected with the hepatitis C virus (HCV) were analyzed. Seventeen patients were identified with genotype (GT) 1b, eleven with GT-1a, nine with GT-2b and four with GT-3a. Two rare subtypes were detected: GT-2j in two patients and GT-2r in one patient. Three patients had mixed infections: one with GT-2k + 2j and two with GT-1b + 2b. This work identifies HCV GTs, 2j, 2k, and 2r for the first time in Mexico.
AB - The HCV 5'UTR, Core/E1, and NS5B regions of samples from fifty patients infected with the hepatitis C virus (HCV) were analyzed. Seventeen patients were identified with genotype (GT) 1b, eleven with GT-1a, nine with GT-2b and four with GT-3a. Two rare subtypes were detected: GT-2j in two patients and GT-2r in one patient. Three patients had mixed infections: one with GT-2k + 2j and two with GT-1b + 2b. This work identifies HCV GTs, 2j, 2k, and 2r for the first time in Mexico.
KW - epidemiology
KW - evolution
KW - genetic variability
KW - hepatitis C virus
KW - virus classification
UR - http://www.scopus.com/inward/record.url?scp=85048051994&partnerID=8YFLogxK
U2 - 10.1002/jmv.25070
DO - 10.1002/jmv.25070
M3 - Artículo
C2 - 29508903
SN - 0146-6615
VL - 90
SP - 1277
EP - 1282
JO - Journal of Medical Virology
JF - Journal of Medical Virology
IS - 7
ER -
