TY - JOUR
T1 - Preotection against Trichinella spiralis induced by purified stage-specific surface antigens of infective larvae
AU - Ortega-Pierres, Guadalupe
AU - Muñiz, Estela
AU - Coral-Vázquez, Ramón
AU - Parkhouse, R. M.E.
PY - 1989/7
Y1 - 1989/7
N2 - The stage-specific surface antigens of the infective larvae of Trichinella spiralis, isolated using an affinity column of monoclonal antibody (Mab) NIM-M1, consisted of four components with molecular weights of 72, 65, 52, and 47 kDa, respectively. These four components may have unique as well as shared structural features and appear to be products of the stichosome. When injected i.p. as an emulsion in complete Freund's adjuvant, the purified antigens induced protection against infection of BALB/c mice with T. spiralis, as assessed by reductions in both the muscle larvae load and the number of adult intestinal worms.
AB - The stage-specific surface antigens of the infective larvae of Trichinella spiralis, isolated using an affinity column of monoclonal antibody (Mab) NIM-M1, consisted of four components with molecular weights of 72, 65, 52, and 47 kDa, respectively. These four components may have unique as well as shared structural features and appear to be products of the stichosome. When injected i.p. as an emulsion in complete Freund's adjuvant, the purified antigens induced protection against infection of BALB/c mice with T. spiralis, as assessed by reductions in both the muscle larvae load and the number of adult intestinal worms.
UR - http://www.scopus.com/inward/record.url?scp=0024323167&partnerID=8YFLogxK
U2 - 10.1007/BF00931167
DO - 10.1007/BF00931167
M3 - Artículo
SN - 0044-3255
VL - 75
SP - 563
EP - 567
JO - Parasitology Research
JF - Parasitology Research
IS - 7
ER -