Portable system for measuring fluorescence signals of biological tissue

Diego Adrian Fabila; Jose Manuel De La Rosa; Suren Stolik; Edgard Moreno; Judith Dominguez; Sergio Miguel Mercado; Tessy Lopez; Mayra Alvarez; Alfonso Arellano; Rodrigo Mercado; Jose Luis Soto

doi:10.1109/TLA.2011.6129696

Portable system for measuring fluorescence signals of biological tissue

Diego Adrian Fabila, Jose Manuel De La Rosa, Suren Stolik, Edgard Moreno, Judith Dominguez, Sergio Miguel Mercado, Tessy Lopez, Mayra Alvarez, Alfonso Arellano, Rodrigo Mercado, Jose Luis Soto

Research output: Contribution to journal › Article › peer-review

Abstract

In this issue the development of a portable system for measuring fluorescence and reflectance signals of biological tissue is presented. It includes a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm and a resolution of 0.5 nm. A light emitting diode at 365 nm with maximum radiant power of 230 mW was used as an excitation source. A bifurcated fiber optic with six 400 μm diameter irradiation fibers and one 400 μm collection fiber is used. The system is powered and controlled by a laptop, avoiding the use of an external power supply. A program to control the light source and to measure the spectra in real time was developed using LabVIEW. Preliminary results of ex vivo and in vivo fluorescence measurements of skin and brain tissues are presented and show that fluorescence and reflection could be used to diagnose and demarcate cancer boundaries.

Original language	English
Article number	6129696
Pages (from-to)	1012-1017
Number of pages	6
Journal	IEEE Latin America Transactions
Volume	9
Issue number	7
DOIs	https://doi.org/10.1109/TLA.2011.6129696
State	Published - Dec 2011

Keywords

Fluorescence
Reflectance
Spectroscopy
Tissue
Ultraviolet

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10.1109/TLA.2011.6129696

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title = "Portable system for measuring fluorescence signals of biological tissue",

abstract = "In this issue the development of a portable system for measuring fluorescence and reflectance signals of biological tissue is presented. It includes a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm and a resolution of 0.5 nm. A light emitting diode at 365 nm with maximum radiant power of 230 mW was used as an excitation source. A bifurcated fiber optic with six 400 μm diameter irradiation fibers and one 400 μm collection fiber is used. The system is powered and controlled by a laptop, avoiding the use of an external power supply. A program to control the light source and to measure the spectra in real time was developed using LabVIEW. Preliminary results of ex vivo and in vivo fluorescence measurements of skin and brain tissues are presented and show that fluorescence and reflection could be used to diagnose and demarcate cancer boundaries.",

keywords = "Fluorescence, Reflectance, Spectroscopy, Tissue, Ultraviolet",

author = "Fabila, {Diego Adrian} and {De La Rosa}, {Jose Manuel} and Suren Stolik and Edgard Moreno and Judith Dominguez and Mercado, {Sergio Miguel} and Tessy Lopez and Mayra Alvarez and Alfonso Arellano and Rodrigo Mercado and Soto, {Jose Luis}",

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doi = "10.1109/TLA.2011.6129696",

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journal = "IEEE Latin America Transactions",

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T1 - Portable system for measuring fluorescence signals of biological tissue

AU - Fabila, Diego Adrian

AU - De La Rosa, Jose Manuel

AU - Stolik, Suren

AU - Moreno, Edgard

AU - Dominguez, Judith

AU - Mercado, Sergio Miguel

AU - Lopez, Tessy

AU - Alvarez, Mayra

AU - Arellano, Alfonso

AU - Mercado, Rodrigo

AU - Soto, Jose Luis

PY - 2011/12

Y1 - 2011/12

N2 - In this issue the development of a portable system for measuring fluorescence and reflectance signals of biological tissue is presented. It includes a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm and a resolution of 0.5 nm. A light emitting diode at 365 nm with maximum radiant power of 230 mW was used as an excitation source. A bifurcated fiber optic with six 400 μm diameter irradiation fibers and one 400 μm collection fiber is used. The system is powered and controlled by a laptop, avoiding the use of an external power supply. A program to control the light source and to measure the spectra in real time was developed using LabVIEW. Preliminary results of ex vivo and in vivo fluorescence measurements of skin and brain tissues are presented and show that fluorescence and reflection could be used to diagnose and demarcate cancer boundaries.

AB - In this issue the development of a portable system for measuring fluorescence and reflectance signals of biological tissue is presented. It includes a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm and a resolution of 0.5 nm. A light emitting diode at 365 nm with maximum radiant power of 230 mW was used as an excitation source. A bifurcated fiber optic with six 400 μm diameter irradiation fibers and one 400 μm collection fiber is used. The system is powered and controlled by a laptop, avoiding the use of an external power supply. A program to control the light source and to measure the spectra in real time was developed using LabVIEW. Preliminary results of ex vivo and in vivo fluorescence measurements of skin and brain tissues are presented and show that fluorescence and reflection could be used to diagnose and demarcate cancer boundaries.

KW - Fluorescence

KW - Reflectance

KW - Spectroscopy

KW - Tissue

KW - Ultraviolet

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DO - 10.1109/TLA.2011.6129696

M3 - Artículo

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VL - 9

SP - 1012

EP - 1017

JO - IEEE Latin America Transactions

JF - IEEE Latin America Transactions

IS - 7

M1 - 6129696

ER -

Portable system for measuring fluorescence signals of biological tissue

Abstract

Keywords

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