TY - JOUR
T1 - Palladium-catalyzed synthesis of quinoxaline derivatives
AU - Wallace, Jeffery M.
AU - Söderberg, Björn C.G.
AU - Tamariz, Joaquín
AU - Akhmedov, Novruz G.
AU - Hurley, Mathew T.
N1 - Funding Information:
This work was supported by research grants from the National Science Foundation (CHE 0611096), the National Institute of General Medical Sciences, National Institutes of Health (RO1 GM57416), and the American Chemical Society Petroleum Research Fund (40665-AC1). NSF-EPSCoR (Grant #1002165R) is gratefully acknowledged for the funding of a 600 MHz Varian Inova NMR and a Thermo-Finnegan LTQ-FT Mass Spectrometer and the NMR and MS facilities in the C. Eugene Bennett Department of Chemistry at West Virginia University. J.T. is grateful to OAS (F54111), CONACYT (250099), and COFAA-IPN (9711220214) for financial support during his sabbatical leave in the USA (1997–1998).
PY - 2008/10/6
Y1 - 2008/10/6
N2 - A palladium-catalyzed reductive N-heteroannulation of enamines derived from 2-nitrobenzenamines forming mixtures of 1,2-dihydroquinoxalines and 3,4-dihydroquinoxalin-2-ones is described. The reactions are performed using bis(dibenzylideneacetone)palladium(0), 1,3-bis(diphenylphosphino)propane, and 1,10-phenanthroline in DMF under 6 atm of carbon monoxide at 70 °C.
AB - A palladium-catalyzed reductive N-heteroannulation of enamines derived from 2-nitrobenzenamines forming mixtures of 1,2-dihydroquinoxalines and 3,4-dihydroquinoxalin-2-ones is described. The reactions are performed using bis(dibenzylideneacetone)palladium(0), 1,3-bis(diphenylphosphino)propane, and 1,10-phenanthroline in DMF under 6 atm of carbon monoxide at 70 °C.
KW - Palladium-catalyzed annulation
KW - Quinoxaline
UR - http://www.scopus.com/inward/record.url?scp=49849092121&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2008.07.083
DO - 10.1016/j.tet.2008.07.083
M3 - Artículo
SN - 0040-4020
VL - 64
SP - 9675
EP - 9684
JO - Tetrahedron
JF - Tetrahedron
IS - 41
ER -