Abstract
A convenient and general method was established to append tri-, hexa-, and nonadentate ligands about an aromatic or aliphatic core. This approach allows a variety of commercially available carboxylic acids to be transformed to their N-tris(hydroxymethyl)methylcarboxamides in one step. The selective activation of the acid functionality to form the polyhydroxylated dendritic cores has been achieved using the acyl transfer agent N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ).
Original language | English |
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Pages (from-to) | 1435-1438 |
Number of pages | 4 |
Journal | Synthesis (Germany) |
Issue number | 10 |
DOIs | |
State | Published - 2000 |
Externally published | Yes |
Keywords
- Amides
- Carboxylic acids
- Coupling
- Dendrimers
- Ligands