Neuropharmacological activity of Solanum nigrum fruit

R. M. Perez G.; J. A. Perez L.; L. M. Garcia D.; H. Sossa M.

doi:10.1016/S0378-8741(98)00059-2

Neuropharmacological activity of Solanum nigrum fruit

R. M. Perez G., J. A. Perez L., L. M. Garcia D., H. Sossa M.

Research output: Contribution to journal › Article › peer-review

166 Scopus citations

Abstract

The ethanol extract of the fruit of Solanum nigrum L. (Solanaceae) was studied for its neuropharmacological properties on experimental animals. On intraperitoneal injection, the extract significantly prolonged pentobarbital-induced sleeping time, produced alteration in the general behavior pattern, reduced exploratory behavior pattern, suppressed the aggressive behavior, affected locomotor activity and reduced spontaneous motility. The observations suggest that the fruit of S. nigrum possesses potential CNS-depressant action.

Original language	English
Pages (from-to)	43-48
Number of pages	6
Journal	Journal of Ethnopharmacology
Volume	62
Issue number	1
DOIs	https://doi.org/10.1016/S0378-8741(98)00059-2
State	Published - Aug 1998
Externally published	Yes

Keywords

Neuropharmacological activity
Solanum nigrum

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10.1016/S0378-8741(98)00059-2

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title = "Neuropharmacological activity of Solanum nigrum fruit",

abstract = "The ethanol extract of the fruit of Solanum nigrum L. (Solanaceae) was studied for its neuropharmacological properties on experimental animals. On intraperitoneal injection, the extract significantly prolonged pentobarbital-induced sleeping time, produced alteration in the general behavior pattern, reduced exploratory behavior pattern, suppressed the aggressive behavior, affected locomotor activity and reduced spontaneous motility. The observations suggest that the fruit of S. nigrum possesses potential CNS-depressant action.",

keywords = "Neuropharmacological activity, Solanum nigrum",

author = "{Perez G.}, {R. M.} and {Perez L.}, {J. A.} and {Garcia D.}, {L. M.} and {Sossa M.}, H.",

year = "1998",

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doi = "10.1016/S0378-8741(98)00059-2",

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AU - Perez L., J. A.

AU - Garcia D., L. M.

AU - Sossa M., H.

PY - 1998/8

Y1 - 1998/8

N2 - The ethanol extract of the fruit of Solanum nigrum L. (Solanaceae) was studied for its neuropharmacological properties on experimental animals. On intraperitoneal injection, the extract significantly prolonged pentobarbital-induced sleeping time, produced alteration in the general behavior pattern, reduced exploratory behavior pattern, suppressed the aggressive behavior, affected locomotor activity and reduced spontaneous motility. The observations suggest that the fruit of S. nigrum possesses potential CNS-depressant action.

AB - The ethanol extract of the fruit of Solanum nigrum L. (Solanaceae) was studied for its neuropharmacological properties on experimental animals. On intraperitoneal injection, the extract significantly prolonged pentobarbital-induced sleeping time, produced alteration in the general behavior pattern, reduced exploratory behavior pattern, suppressed the aggressive behavior, affected locomotor activity and reduced spontaneous motility. The observations suggest that the fruit of S. nigrum possesses potential CNS-depressant action.

KW - Neuropharmacological activity

KW - Solanum nigrum

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U2 - 10.1016/S0378-8741(98)00059-2

DO - 10.1016/S0378-8741(98)00059-2

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JO - Journal of Ethnopharmacology

JF - Journal of Ethnopharmacology

IS - 1

ER -

Neuropharmacological activity of Solanum nigrum fruit

Abstract

Keywords

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