TY - JOUR
T1 - Natural products; pharmacological importance of family Cucurbitaceae
T2 - A brief review
AU - Shah, Syed Shoaib Ahmad
AU - Hussain, M. Ijaz
AU - Aslam, M. Kashif
AU - Rivera, Gildardo
PY - 2014
Y1 - 2014
N2 - Compounds derived from nature have played a major role in drug discovery. They became the basis for the development of new pharmaceuticals. In this scope, family Cucurbitaceae is a prominent source of secondary metabolites, mainly triterpenoids. In this paper, we provide a brief review of cucurbitane metabolites that exhibit an extensive range of biological actions specifically antidiabetic, anti-inflammatory, cytotoxic, hepatoprotective, and antiparasitic effects.
AB - Compounds derived from nature have played a major role in drug discovery. They became the basis for the development of new pharmaceuticals. In this scope, family Cucurbitaceae is a prominent source of secondary metabolites, mainly triterpenoids. In this paper, we provide a brief review of cucurbitane metabolites that exhibit an extensive range of biological actions specifically antidiabetic, anti-inflammatory, cytotoxic, hepatoprotective, and antiparasitic effects.
KW - Antibacterial
KW - Antiparasitic
KW - Cucurbitaceae
KW - Momordica
KW - Natural products
KW - Pharmacological activity
UR - http://www.scopus.com/inward/record.url?scp=84906909687&partnerID=8YFLogxK
U2 - 10.2174/1389557514666140820113055
DO - 10.2174/1389557514666140820113055
M3 - Artículo
SN - 1389-5575
VL - 14
SP - 694
EP - 705
JO - Mini-Reviews in Medicinal Chemistry
JF - Mini-Reviews in Medicinal Chemistry
IS - 8
ER -