Nanopartículas lipídicas sólidas

Leopoldo Villafuerte Robles; Beatriz García F.; María De Lourdes Garzón S.; Alejandra Hernández L.; María Luisa Vázquez R.

Nanopartículas lipídicas sólidas

Translated title of the contribution: Solid lipid nanoparticles

Leopoldo Villafuerte Robles, Beatriz García F., María De Lourdes Garzón S., Alejandra Hernández L., María Luisa Vázquez R.

Escuela Nacional de Ciencias Biológicas (ENCB)

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

solid lipid nanoparticles (SLN) were developed as an alternative carrier system to emulsions, liposomes and polymeric nanoparticles. Particulate structures based in solid lipids such as "solid lipid nanoparticles" (SLN), "nanostructurated lipid carriers" (NLC), lipid-coated nanoparticles (LNPs) and "lipid drug conjugate nanoparticles" (LDC) are presented. Aspects of the physical stability and the characterization of SLN are discussed through parameters such as particle size and zeta potential, the measurement of crystallinity and the lipid modification. These and other analytical methods such as differential scanning calorimetry and X-ray scattering, nuclear magnetic resonance and electron spin resonance and their use in SLN are briefly described.

Translated title of the contribution	Solid lipid nanoparticles
Original language	Spanish
Pages (from-to)	38-52
Number of pages	15
Journal	Revista Mexicana de Ciencias Farmaceuticas
Volume	39
Issue number	1
State	Published - Jan 2008

Cite this

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title = "Nanopart{\'i}culas lip{\'i}dicas s{\'o}lidas",

abstract = "solid lipid nanoparticles (SLN) were developed as an alternative carrier system to emulsions, liposomes and polymeric nanoparticles. Particulate structures based in solid lipids such as {"}solid lipid nanoparticles{"} (SLN), {"}nanostructurated lipid carriers{"} (NLC), lipid-coated nanoparticles (LNPs) and {"}lipid drug conjugate nanoparticles{"} (LDC) are presented. Aspects of the physical stability and the characterization of SLN are discussed through parameters such as particle size and zeta potential, the measurement of crystallinity and the lipid modification. These and other analytical methods such as differential scanning calorimetry and X-ray scattering, nuclear magnetic resonance and electron spin resonance and their use in SLN are briefly described.",

keywords = "Lipid drug conjugate nanoparticles, Lipid-coated nanoparticles, Nanoparticle characterization, Nanostructurated lipid carriers, Solid lipid nanoparticles, Stability",

author = "{Villafuerte Robles}, Leopoldo and {Garc{\'i}a F.}, Beatriz and {Garz{\'o}n S.}, {Mar{\'i}a De Lourdes} and {Hern{\'a}ndez L.}, Alejandra and {V{\'a}zquez R.}, {Mar{\'i}a Luisa}",

year = "2008",

month = jan,

language = "Espa{\~n}ol",

volume = "39",

pages = "38--52",

journal = "Revista Mexicana de Ciencias Farmaceuticas",

issn = "1027-3956",

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}

TY - JOUR

T1 - Nanopartículas lipídicas sólidas

AU - Villafuerte Robles, Leopoldo

AU - García F., Beatriz

AU - Garzón S., María De Lourdes

AU - Hernández L., Alejandra

AU - Vázquez R., María Luisa

PY - 2008/1

Y1 - 2008/1

N2 - solid lipid nanoparticles (SLN) were developed as an alternative carrier system to emulsions, liposomes and polymeric nanoparticles. Particulate structures based in solid lipids such as "solid lipid nanoparticles" (SLN), "nanostructurated lipid carriers" (NLC), lipid-coated nanoparticles (LNPs) and "lipid drug conjugate nanoparticles" (LDC) are presented. Aspects of the physical stability and the characterization of SLN are discussed through parameters such as particle size and zeta potential, the measurement of crystallinity and the lipid modification. These and other analytical methods such as differential scanning calorimetry and X-ray scattering, nuclear magnetic resonance and electron spin resonance and their use in SLN are briefly described.

AB - solid lipid nanoparticles (SLN) were developed as an alternative carrier system to emulsions, liposomes and polymeric nanoparticles. Particulate structures based in solid lipids such as "solid lipid nanoparticles" (SLN), "nanostructurated lipid carriers" (NLC), lipid-coated nanoparticles (LNPs) and "lipid drug conjugate nanoparticles" (LDC) are presented. Aspects of the physical stability and the characterization of SLN are discussed through parameters such as particle size and zeta potential, the measurement of crystallinity and the lipid modification. These and other analytical methods such as differential scanning calorimetry and X-ray scattering, nuclear magnetic resonance and electron spin resonance and their use in SLN are briefly described.

KW - Lipid drug conjugate nanoparticles

KW - Lipid-coated nanoparticles

KW - Nanoparticle characterization

KW - Nanostructurated lipid carriers

KW - Solid lipid nanoparticles

KW - Stability

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M3 - Artículo de revisión

SN - 1027-3956

VL - 39

SP - 38

EP - 52

JO - Revista Mexicana de Ciencias Farmaceuticas

JF - Revista Mexicana de Ciencias Farmaceuticas

IS - 1

ER -

Nanopartículas lipídicas sólidas

Abstract

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