TY - JOUR
T1 - Nanopartículas como transportadores de fármacos
T2 - Una herramienta prometedora contra la tuberculosis
AU - Luna-Herrera, Julieta
AU - Pérez-Martínez, Damián Eduardo
AU - Barradas-Hernández, Virginia Margarita
AU - Zenteno-Cuevas, Roberto
N1 - Publisher Copyright:
© 2021, Instituto Nacional de Salud. All rights reserved.
PY - 2021
Y1 - 2021
N2 - The World Health Organization (WHO) places Tuberculosis (TB) as one of the most important health problems today. According to the WHO, this disease requires novel actions to control its expansion and, in this way, achieve one of the goals established in the sustainable development goals: to reduce TB morbidity and incidence by 2030 and regain control. To achieve this goal, the tools currently used for diagnosis and treatment are no longer adequate. In this sense, it is necessary to develop new drugs and vaccines, as well as novel drug administration procedures that generate a better response, reduce times, and optimize treatments. Nanotechnology has incorporated in recent years a considerable number of new tools that significantly increase the diversity of mechanisms for the administration of anti-tuberculosis drugs. Therefore, the present review briefly describes the current state of drug resistance in tuberculosis, as well as the general characteristics of nanoparticles being evaluated as tools to transport new antibiotics against tuberculosis.
AB - The World Health Organization (WHO) places Tuberculosis (TB) as one of the most important health problems today. According to the WHO, this disease requires novel actions to control its expansion and, in this way, achieve one of the goals established in the sustainable development goals: to reduce TB morbidity and incidence by 2030 and regain control. To achieve this goal, the tools currently used for diagnosis and treatment are no longer adequate. In this sense, it is necessary to develop new drugs and vaccines, as well as novel drug administration procedures that generate a better response, reduce times, and optimize treatments. Nanotechnology has incorporated in recent years a considerable number of new tools that significantly increase the diversity of mechanisms for the administration of anti-tuberculosis drugs. Therefore, the present review briefly describes the current state of drug resistance in tuberculosis, as well as the general characteristics of nanoparticles being evaluated as tools to transport new antibiotics against tuberculosis.
KW - Anti-Infective Agents
KW - Antimicrobial Drug Resistance
KW - Biological Transport
KW - Nanoparticles
KW - Tuberculosis
UR - http://www.scopus.com/inward/record.url?scp=85111789055&partnerID=8YFLogxK
U2 - 10.17843/rpmesp.2021.381.6156
DO - 10.17843/rpmesp.2021.381.6156
M3 - Artículo
C2 - 34190907
AN - SCOPUS:85111789055
SN - 1726-4634
VL - 38
SP - 143
EP - 152
JO - Revista Peruana de Medicina Experimental y Salud Publica
JF - Revista Peruana de Medicina Experimental y Salud Publica
IS - 1
ER -