Molecular characterization and antifungal susceptibility of the Candida parapsilosis species complex of clinical isolates from Monterrey, Mexico

Rogelio De J. Treviño-Rangel, Elvira Garza-González, J. Gerardo González, Virgilio Bocanegra-García, Jorge M. Llaca, Gloria M. González

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24 Scopus citations

Abstract

Recently, it was proposed that the opportunistic yeast pathogen Candida parapsilosis was a complex composed of the following three species: Candida parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. A set of 344 clinical isolates of Candida parapsilosis from Monterrey, Mexico was re-identified by RFLP. Their antifungal susceptibility to fluconazole, caspofungin, anidulafungin and micafungin was determined using the Clinical and Laboratory Standards Institute M27-A3 protocol. Candida parapsilosis sensu stricto was the most frequent species, and was the only one which showed resistance to antifungals.

Original languageEnglish
Pages (from-to)781-784
Number of pages4
JournalMedical Mycology
Volume50
Issue number7
DOIs
StatePublished - Oct 2012

Keywords

  • Antifungal susceptibility
  • Candida metapsilosis
  • Candida orthopsilosis
  • Candida parapsilosis
  • Candidosis

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