Microsatellite polymorphism in intron 1 of the bovine myostatin gene

Xochitl F. De La Rosa-Reyna; Mario A. Rodríguez Pérez; Ana M. Sifuentes-Rincón

doi:10.1007/BF03194599

Microsatellite polymorphism in intron 1 of the bovine myostatin gene

Xochitl F. De La Rosa-Reyna, Mario A. Rodríguez Pérez, Ana M. Sifuentes-Rincón

Centro de Biotecnología Genómica (CBG)

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5 Scopus citations

Abstract

Microsatellites within genes have become important because of their association with genetic diseases in humans. A novel microsatellite was identified in the first intron of the bovine myostatin gene. It is characterized by a mononucleotide core motif that exhibits polymorphic sequence variants (from 12 to 21 repeats) within and between some bovine breeds. Structural analysis of the microsatellite region in bovines as well as in closely related species permitted to trace the possible mechanisms for its structural evolution across the order Artiodactyla.

Original language	English
Pages (from-to)	55-57
Number of pages	3
Journal	Journal of Applied Genetics
Volume	47
Issue number	1
DOIs	https://doi.org/10.1007/BF03194599
State	Published - 2006

Keywords

Bovine double-muscling
Myostatin
SSRs

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10.1007/BF03194599

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title = "Microsatellite polymorphism in intron 1 of the bovine myostatin gene",

abstract = "Microsatellites within genes have become important because of their association with genetic diseases in humans. A novel microsatellite was identified in the first intron of the bovine myostatin gene. It is characterized by a mononucleotide core motif that exhibits polymorphic sequence variants (from 12 to 21 repeats) within and between some bovine breeds. Structural analysis of the microsatellite region in bovines as well as in closely related species permitted to trace the possible mechanisms for its structural evolution across the order Artiodactyla.",

keywords = "Bovine double-muscling, Myostatin, SSRs",

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AU - De La Rosa-Reyna, Xochitl F.

AU - Rodríguez Pérez, Mario A.

AU - Sifuentes-Rincón, Ana M.

PY - 2006

Y1 - 2006

N2 - Microsatellites within genes have become important because of their association with genetic diseases in humans. A novel microsatellite was identified in the first intron of the bovine myostatin gene. It is characterized by a mononucleotide core motif that exhibits polymorphic sequence variants (from 12 to 21 repeats) within and between some bovine breeds. Structural analysis of the microsatellite region in bovines as well as in closely related species permitted to trace the possible mechanisms for its structural evolution across the order Artiodactyla.

AB - Microsatellites within genes have become important because of their association with genetic diseases in humans. A novel microsatellite was identified in the first intron of the bovine myostatin gene. It is characterized by a mononucleotide core motif that exhibits polymorphic sequence variants (from 12 to 21 repeats) within and between some bovine breeds. Structural analysis of the microsatellite region in bovines as well as in closely related species permitted to trace the possible mechanisms for its structural evolution across the order Artiodactyla.

KW - Bovine double-muscling

KW - Myostatin

KW - SSRs

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U2 - 10.1007/BF03194599

DO - 10.1007/BF03194599

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SP - 55

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JO - Journal of Applied Genetics

JF - Journal of Applied Genetics

IS - 1

ER -

Microsatellite polymorphism in intron 1 of the bovine myostatin gene

Abstract

Keywords

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