TY - JOUR
T1 - Measurement of local gas holdup in bubble columns via a non-isokinetic withdrawal method
AU - García-Salas, Sergio
AU - Orozco-Alvarez, Carlos
AU - Porter, R. Michael
AU - Thalasso, Frederic
N1 - Funding Information:
The authors acknowledge the financial support of the Instituto Mexicano del Petróleo (IMP) through a FIES project (FIES-98-107-VI) and CONACyT (México). The authors also thank C. I. Hernández González for his technical assistance and L. Dendooven and L. B. Flores-Cotera for their critical reading of the manuscript. S. García-Salas was holder of a grant from COFAA-I.P.N. and SUPERA and gratefully acknowledges the COTEPABE-I.P.N., México.
PY - 2005/12
Y1 - 2005/12
N2 - An inexpensive method was developed to measure local gas holdup based on withdrawal of the air-liquid dispersion in bioreactors under non-isokinetic conditions. The method was tested with several suction probe designs and withdrawal pressures using coalescing and non-coalescing model media as well as during yeast fermentations. Simultaneously, gas holdup was measured manometrically. With a straight end probe and vacuum pressure of 3 kPa, local gas holdup measurements presented a relative error <6% compared to the manometric method, independently of the media composition. This method was used to characterize local gas holdup in a bubble column. Two new parameters are proposed to characterize non-gassed volume and gas holdup homogeneity.
AB - An inexpensive method was developed to measure local gas holdup based on withdrawal of the air-liquid dispersion in bioreactors under non-isokinetic conditions. The method was tested with several suction probe designs and withdrawal pressures using coalescing and non-coalescing model media as well as during yeast fermentations. Simultaneously, gas holdup was measured manometrically. With a straight end probe and vacuum pressure of 3 kPa, local gas holdup measurements presented a relative error <6% compared to the manometric method, independently of the media composition. This method was used to characterize local gas holdup in a bubble column. Two new parameters are proposed to characterize non-gassed volume and gas holdup homogeneity.
KW - Bioreactor
KW - Bubble column
KW - Coalescing
KW - Fermentation
KW - Hydrodynamics
KW - Non-coalescing media
UR - http://www.scopus.com/inward/record.url?scp=24344475578&partnerID=8YFLogxK
U2 - 10.1016/j.ces.2005.06.010
DO - 10.1016/j.ces.2005.06.010
M3 - Artículo
AN - SCOPUS:24344475578
SN - 0009-2509
VL - 60
SP - 6929
EP - 6938
JO - Chemical Engineering Science
JF - Chemical Engineering Science
IS - 24
ER -