TY - JOUR
T1 - La química medicinal (química-farmacéutica) en la salud pública
T2 - Nuestra experiencia en el diseño de moléculas con potencial terapéutico
AU - Sánchez, Gildardo Rivera
AU - Palos, Isidro
AU - Mireles-Martínez, Maribel
AU - Rosas-García, Ninfa M.
AU - Bocanegra-García, Virgilio
N1 - Publisher Copyright:
© 2014, Asociacion Farmaceutica Mexicana A.C. All rights reserved.
PY - 2014
Y1 - 2014
N2 - This paper briefly describes the progress that our research group has achieved in the design, synthesis and biological evaluation of new potential therapeutic molecules for public health problems such as obesity, cancer, tuberculosis, and American trypanosomiasis or Chagas disease. We briefly reviewed the relevance of each of these diseases, the drugs that have been used for treatment and those that are in development. Furthermore, we describe the rational design and synthesis strategies conducted by our research group, which have been focused on the development of new compounds with biological activity as potential anti-obesity, anti-cancer, anti-tuberculosis, and anti-trypanosomiasis agents.
AB - This paper briefly describes the progress that our research group has achieved in the design, synthesis and biological evaluation of new potential therapeutic molecules for public health problems such as obesity, cancer, tuberculosis, and American trypanosomiasis or Chagas disease. We briefly reviewed the relevance of each of these diseases, the drugs that have been used for treatment and those that are in development. Furthermore, we describe the rational design and synthesis strategies conducted by our research group, which have been focused on the development of new compounds with biological activity as potential anti-obesity, anti-cancer, anti-tuberculosis, and anti-trypanosomiasis agents.
KW - Cancer
KW - Medicinal chemistry
KW - Obesity
KW - Trypanosomiasis
KW - Tuberculosis
UR - http://www.scopus.com/inward/record.url?scp=84975509509&partnerID=8YFLogxK
M3 - Artículo
SN - 1027-3956
VL - 45
SP - 15
EP - 25
JO - Revista Mexicana de Ciencias Farmaceuticas
JF - Revista Mexicana de Ciencias Farmaceuticas
IS - 1
ER -