© 2018 Flacso Mexico. All rights reserved. The objective of the investigation is to study the effectiveness of Mexican state police through the impact of organizational design and the development of the human factor. For this, the method was based on multivariate causal analysis. The results indicate that the specialization of police functions, lack of agents, infiltration of crime, lack of loyalty and negligence are statistically significant in their effectiveness. Therefore, an index is proposed, considering the number of homicides, stolen auto insured, citizen perception of insecurity and citizen rating of police action, which can serve to improve the effectiveness of the police.