Inverse Electron Demand Diels-Alder-Type Heterocycle Syntheses with 1,2,3-Triazine 1-Oxides: Expanded Versatility

Medicine & Life Sciences

• 5-aminopyrazole 100%
• n-butyl nitrite 92%
• pyrazolo(1,5-a)pyrimidine 91%
• Pyridines 81%
• Amidines 78%
• Cycloaddition Reaction 75%
• Heterocyclic Compounds 74%
• Nitriles 71%
• Triazines 70%
• Pyrimidines 64%
• Oxides 54%
• Electrons 36%
• Temperature 32%

Physics & Astronomy

• pyrimidines 62%
• versatility 50%
• heterocyclic compounds 40%
• Diels-Alder reactions 39%
• synthesis 32%
• nitriles 32%
• nitrites 31%
• pyridines 28%
• oxides 28%
• electrons 19%
• room temperature 12%

Chemistry

• 1,2,3-triazine 78%
• Pyrimidine 40%
• Amidine 27%
• Nucleophilic Addition 24%
• Electron Particle 24%
• Heterocyclic Compound 23%
• Nitrite 21%
• Diels-Alder Reaction 21%
• Nitrile 20%
• Pyridine 16%
• Modification 12%
• Ambient Reaction Temperature 12%
• Reaction Yield 9%