TY - JOUR
T1 - Impact of the modification of a cleaning and disinfection method of mechanical ventilators of COVID-19 patients and ventilator-associated pneumonia
T2 - One year of experience
AU - Cureño-Díaz, Monica Alethia
AU - Durán-Manuel, Emilio Mariano
AU - Cruz-Cruz, Clemente
AU - Ibáñez-Cervantes, Gabriela
AU - Rojo-Gutiérrez, María Isabel
AU - Moncayo-Coello, Carol Vivian
AU - Loyola-Cruz, Miguel Ángel
AU - Castro-Escarpulli, Graciela
AU - Hernández, Dulce Milagros Razo Blanco
AU - Bello-López, Juan Manuel
N1 - Publisher Copyright:
© 2021 Association for Professionals in Infection Control and Epidemiology, Inc.
PY - 2021/12
Y1 - 2021/12
N2 - Background: Mechanical ventilators are essential biomedical devices for the respiratory support of patients with SARS-CoV-2 infection. These devices can be transmitters of bacterial pathogens. Therefore, it is necessary to implement effective disinfection procedures. The aim of this work was to show the impact of the modification of a cleaning and disinfection method of mechanical ventilators of patients with SARS-CoV-2 and ventilator-associated pneumonia. Methods: A total of 338 mechanical ventilators of patients infected with SARS-CoV-2 and ESKAPE bacteria were divided in two groups. Group A and B were subjected to cleaning and disinfection with superoxidation solution-Cl/enzymatic detergent and isopropyl alcohol, respectively. Both groups were cultured for the detection of ESKAPE bacteria. The isolates were subjected to tests for identification, resistance, adherence, and genomic typing. Results: Contamination rates of 21.6% (n = 36) were identified in group A. The inspiratory limb was the circuit involved in most cases of postdisinfection contamination. Acinetobacter baumanni, Pseudomonas aeruginosa, and multi-resistant Klebsiella pneumoniae were the pathogens involved in the contamination cases. The pathogens were highly adherent and in the case of A. baumanni, clonal dispersion was detected in 14 ventilators. Disinfection with enzymatic detergents allows a 100% reduction in contamination rates. Conclusions: The implementation of cleaning and disinfection with enzymatic detergents/isopropyl alcohol of mechanical ventilators of patients with SARS-CoV-2 and ESKAPE bacteria had a positive impact on postdisinfection microbial contamination rates.
AB - Background: Mechanical ventilators are essential biomedical devices for the respiratory support of patients with SARS-CoV-2 infection. These devices can be transmitters of bacterial pathogens. Therefore, it is necessary to implement effective disinfection procedures. The aim of this work was to show the impact of the modification of a cleaning and disinfection method of mechanical ventilators of patients with SARS-CoV-2 and ventilator-associated pneumonia. Methods: A total of 338 mechanical ventilators of patients infected with SARS-CoV-2 and ESKAPE bacteria were divided in two groups. Group A and B were subjected to cleaning and disinfection with superoxidation solution-Cl/enzymatic detergent and isopropyl alcohol, respectively. Both groups were cultured for the detection of ESKAPE bacteria. The isolates were subjected to tests for identification, resistance, adherence, and genomic typing. Results: Contamination rates of 21.6% (n = 36) were identified in group A. The inspiratory limb was the circuit involved in most cases of postdisinfection contamination. Acinetobacter baumanni, Pseudomonas aeruginosa, and multi-resistant Klebsiella pneumoniae were the pathogens involved in the contamination cases. The pathogens were highly adherent and in the case of A. baumanni, clonal dispersion was detected in 14 ventilators. Disinfection with enzymatic detergents allows a 100% reduction in contamination rates. Conclusions: The implementation of cleaning and disinfection with enzymatic detergents/isopropyl alcohol of mechanical ventilators of patients with SARS-CoV-2 and ESKAPE bacteria had a positive impact on postdisinfection microbial contamination rates.
KW - Bacterial contamination
KW - ESKAPE bacteria
KW - Medical devices
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85117130224&partnerID=8YFLogxK
U2 - 10.1016/j.ajic.2021.09.012
DO - 10.1016/j.ajic.2021.09.012
M3 - Artículo
C2 - 34547360
AN - SCOPUS:85117130224
SN - 0196-6553
VL - 49
SP - 1474
EP - 1480
JO - American Journal of Infection Control
JF - American Journal of Infection Control
IS - 12
ER -