Abstract
Hypoglycemic activity-guided fractionation together with chemical analysis led to the isolation of one guaianolide (lactucin-8-O-methylacrylate) from the chloroform extract of the dried fruits of Parmentiera edulis. Identification was based on spectroscopic methods. The compounds lowers blood sugar levels after administration to alloxan-diabetic mice. (C) 2000 Elsevier Science Ireland Ltd.
Original language | English |
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Pages (from-to) | 391-394 |
Number of pages | 4 |
Journal | Journal of Ethnopharmacology |
Volume | 71 |
Issue number | 3 |
DOIs | |
State | Published - 2000 |
Externally published | Yes |
Keywords
- Guaianolide
- Hypoglycemic activity
- Lactucin-8-O-methylacrylate
- Parmentiera edulis
- Sesquiterpene lactone