Human Trypanosoma cruzi infection and seropositivity in dogs, Mexico

Jose G. Estrada-Franco; Vandanajay Bhatia; Hector Diaz-Albiter; Laucel Ochoa-Garcia; Alberto Barbabosa; Juan C. Vazquez-Chagoyan; Miguel A. Martinez-Perez; Carmen Guzman-Bracho; Nisha Garg

doi:10.3201/eid1204.050450

Human Trypanosoma cruzi infection and seropositivity in dogs, Mexico

Jose G. Estrada-Franco, Vandanajay Bhatia, Hector Diaz-Albiter, Laucel Ochoa-Garcia, Alberto Barbabosa, Juan C. Vazquez-Chagoyan, Miguel A. Martinez-Perez, Carmen Guzman-Bracho, Nisha Garg

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Abstract

We used 5 diagnostic tests in a cross-sectional investigation of the prevalence of Trypanosoma cruzi in Tejupilco municipality, State of Mexico, Mexico. Our findings showed a substantial prevalence of immunoglobulin G (IgG) and IgM antibodies to T. cruzi in human (n = 293, IgG 2.05%, IgM 5.5%, both 7.1%) and dog (n = 114, IgG 15.8%, IgM 11.4%, both 21%) populations. We also found antibodies to T. cruzi (n = 80, IgG 10%, IgM 15%, both 17.5%) in dogs from Toluca, an area previously considered free of T. cruzi. Our data demonstrate the need for active epidemiologic surveillance programs in these regions. A direct correlation (r² = 0.955) of seropositivity between humans and dogs suggests that seroanalysis in dogs may help identify the human prevalence of T. cruzi infection in these areas.

Original language	English
Pages (from-to)	624-630
Number of pages	7
Journal	Emerging Infectious Diseases
Volume	12
Issue number	4
DOIs	https://doi.org/10.3201/eid1204.050450
State	Published - Apr 2006
Externally published	Yes

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title = "Human Trypanosoma cruzi infection and seropositivity in dogs, Mexico",

abstract = "We used 5 diagnostic tests in a cross-sectional investigation of the prevalence of Trypanosoma cruzi in Tejupilco municipality, State of Mexico, Mexico. Our findings showed a substantial prevalence of immunoglobulin G (IgG) and IgM antibodies to T. cruzi in human (n = 293, IgG 2.05%, IgM 5.5%, both 7.1%) and dog (n = 114, IgG 15.8%, IgM 11.4%, both 21%) populations. We also found antibodies to T. cruzi (n = 80, IgG 10%, IgM 15%, both 17.5%) in dogs from Toluca, an area previously considered free of T. cruzi. Our data demonstrate the need for active epidemiologic surveillance programs in these regions. A direct correlation (r2 = 0.955) of seropositivity between humans and dogs suggests that seroanalysis in dogs may help identify the human prevalence of T. cruzi infection in these areas.",

author = "Estrada-Franco, {Jose G.} and Vandanajay Bhatia and Hector Diaz-Albiter and Laucel Ochoa-Garcia and Alberto Barbabosa and Vazquez-Chagoyan, {Juan C.} and Martinez-Perez, {Miguel A.} and Carmen Guzman-Bracho and Nisha Garg",

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AU - Estrada-Franco, Jose G.

AU - Bhatia, Vandanajay

AU - Diaz-Albiter, Hector

AU - Ochoa-Garcia, Laucel

AU - Barbabosa, Alberto

AU - Vazquez-Chagoyan, Juan C.

AU - Martinez-Perez, Miguel A.

AU - Guzman-Bracho, Carmen

AU - Garg, Nisha

PY - 2006/4

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Human Trypanosoma cruzi infection and seropositivity in dogs, Mexico

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