Abstract
A synthesis of the natural terpenoid sporilactone (±)-andirolactone (1) is described. Condensation of dimethyl malonate (9) with 1-acetyl-4-methyl-3-cyclohexen-1-ol (3), prepared by Diels-Alder reaction of olefin 5 and isoprene (4), and thermal decarboxylation of the resulting spirolactone 10, afforded 1 in 46% overall yield.
Original language | English |
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Pages (from-to) | 375-377 |
Number of pages | 3 |
Journal | Synthesis (Germany) |
Issue number | 4 |
DOIs | |
State | Published - 1993 |