High Yield Synthesis of Curcumin and Symmetric Curcuminoids: A “Click” and “Unclick” Chemistry Approach

Medicine & Life Sciences

• acetylacetone 100%
• Click Chemistry 83%
• Diarylheptanoids 79%
• Curcumin 58%
• boron trifluoride 53%
• bis(4-hydroxycinnamoyl)methane 45%
• demethoxycurcumin 44%
• Aluminum Hydroxide 35%
• Spices 34%
• Curcuma 33%
• Crystallization 31%
• Oxides 30%
• Silicon Dioxide 29%
• Powders 25%
• Therapeutics 4%

Chemistry

• Curcumin 58%
• Chemistry 29%
• Bisdemethoxycurcumin 24%
• Reaction Yield 20%
• Cleavage 10%
• Boron Trifluoride 8%
• Acetylacetone 8%
• Crystallization 5%
• Amorphous Material 5%
• Purification 4%
• Oxide 3%
• Purity 3%

Physics & Astronomy

• chemistry 44%
• synthesis 36%
• cleavage 15%
• boron fluorides 12%
• methodology 11%
• acetylacetone 11%
• purification 8%
• aluminum oxides 5%
• crystallization 5%
• silicon dioxide 5%
• oxides 4%