Fischer indole synthesis of (β-Oxo)Indol-3-Yl Ketones using protected 1,3-Dicarbonyl compounds

Luis G. Zepeda, Martha S. Morales-Rios, Pedro Joseph-Nathan

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The condensation products of 4-methoxyphenylhydrazine and 3, 3-dimethylenedithio-5-oxyaldehydes undergo Fischer cyclization to the corresponding indoles. The carbonyl-protecting group can be removed from the latter with formation of (β-oxo)indol-3-yl ketones.

Original languageEnglish
Pages (from-to)3243-3256
Number of pages14
JournalSynthetic Communications
Volume22
Issue number22
DOIs
StatePublished - 1 Dec 1992
Externally publishedYes

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