TY - JOUR
T1 - Factores de virulencia en cepas de Aeromonas aisladas de pacientes con enfermedad diarreica aguda en Cuba
AU - Fariñas, Laura Bravo
AU - Suárez, Susana San Germán
AU - Abreu, Anabel Fernández
AU - Álvarez, Margarita Ramírez
AU - Díaz, Luis Morier
AU - Andreu, Carlos Fernández
AU - Cabrera Rodríguez, Luis E.
AU - Escarpulli, Graciela Castro
AU - Ginarte, Yudith Ledo
AU - Martínez, Yusleidy Correa
AU - Fernández, Fidel Núñez
AU - Infante, Yanaika Cruz
PY - 2008
Y1 - 2008
N2 - OBJECTIVE: A study was carried out in Aeromonas strains isolated from patients with acute diarrheas in Cuba to find out the phenotypical expression of the cytotoxin and the enterotoxin as virulence factors. METHODS: Forty six strains of the genus Aeromonas: (A. hydrophila, A. veronii bv sobria, A. caviae, A. veronii bv veronii and Aeromonas spp.) isolated from stool specimens taken form patients with acute diarrheal disease were studied from 2005 to 2006. All the strains had their pattern of antimicrobial susceptibility pattern identified. The phenotypic expression of the cytotoxin and the enterotoxin in the Vero cell line was checked. RESULTS: It was demonstrated that 91,31 % of the strains showed cytotoxic activity and 43,48 % of them enterotoxic activity. Regarding multiresistant strains, 93,75 % presented with at least one of the studied virulence factors. CONCLUSIONS: these results proved that the two researched virulence factors did exist in the studied strains, thus contributing to the many efforts that are being made to learn about the mechanisms of enteropathogenicity of this bacterial genus.
AB - OBJECTIVE: A study was carried out in Aeromonas strains isolated from patients with acute diarrheas in Cuba to find out the phenotypical expression of the cytotoxin and the enterotoxin as virulence factors. METHODS: Forty six strains of the genus Aeromonas: (A. hydrophila, A. veronii bv sobria, A. caviae, A. veronii bv veronii and Aeromonas spp.) isolated from stool specimens taken form patients with acute diarrheal disease were studied from 2005 to 2006. All the strains had their pattern of antimicrobial susceptibility pattern identified. The phenotypic expression of the cytotoxin and the enterotoxin in the Vero cell line was checked. RESULTS: It was demonstrated that 91,31 % of the strains showed cytotoxic activity and 43,48 % of them enterotoxic activity. Regarding multiresistant strains, 93,75 % presented with at least one of the studied virulence factors. CONCLUSIONS: these results proved that the two researched virulence factors did exist in the studied strains, thus contributing to the many efforts that are being made to learn about the mechanisms of enteropathogenicity of this bacterial genus.
KW - Aeromonas
KW - Cytotoxicity
KW - Enterotoxigenicity
UR - http://www.scopus.com/inward/record.url?scp=56649105081&partnerID=8YFLogxK
M3 - Artículo
SN - 0375-0760
VL - 60
SP - 130
EP - 135
JO - Revista Cubana de Medicina Tropical
JF - Revista Cubana de Medicina Tropical
IS - 2
ER -