Experimental tests in tissue phantoms of a photoirradiation system with optical dosimetry for photodynamic therapy

L. Hernández-Quintanar; S. Stolik; J. M. De La Rosa

doi:10.1109/CONIELECOMP.2012.6189879

Experimental tests in tissue phantoms of a photoirradiation system with optical dosimetry for photodynamic therapy

L. Hernández-Quintanar, S. Stolik, J. M. De La Rosa

Research output: Contribution to conference › Paper › peer-review

Abstract

Photodynamic therapy involves the administration of a photosensitizer drug followed by a local illumination with light of specific wavelength. In the presence of oxygen molecules, the light illumination of photosensitizer can activate the production of reactive oxygen species which produce the death of malignant cells. Light dose is an important factor for reach an effective therapy. In this work it is presented an irradiation system which allows the application of radiation at 630 nm for 5-AminoLevulinic Acid superficial Photodynamic Therapy using as a light source, a light emitting diode and an automatic control of output optical power using the results of a model of distribution of radiation in depth for different optical properties. The system was tested in tissue phantoms which allow a more controlled environment than test in vivo or in vitro.

Original language	English
Pages	45-49
Number of pages	5
DOIs	https://doi.org/10.1109/CONIELECOMP.2012.6189879
State	Published - 2012
Event	22nd Annual International Conference on Electronics, Communications and Computers, CONIELECOMP 2012 - Cholula, Mexico Duration: 27 Feb 2012 → 29 Feb 2012

Conference

Conference	22nd Annual International Conference on Electronics, Communications and Computers, CONIELECOMP 2012
Country/Territory	Mexico
City	Cholula
Period	27/02/12 → 29/02/12

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10.1109/CONIELECOMP.2012.6189879

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Hernández-Quintanar, L., Stolik, S., & De La Rosa, J. M. (2012). Experimental tests in tissue phantoms of a photoirradiation system with optical dosimetry for photodynamic therapy. 45-49. Paper presented at 22nd Annual International Conference on Electronics, Communications and Computers, CONIELECOMP 2012, Cholula, Mexico. https://doi.org/10.1109/CONIELECOMP.2012.6189879

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abstract = "Photodynamic therapy involves the administration of a photosensitizer drug followed by a local illumination with light of specific wavelength. In the presence of oxygen molecules, the light illumination of photosensitizer can activate the production of reactive oxygen species which produce the death of malignant cells. Light dose is an important factor for reach an effective therapy. In this work it is presented an irradiation system which allows the application of radiation at 630 nm for 5-AminoLevulinic Acid superficial Photodynamic Therapy using as a light source, a light emitting diode and an automatic control of output optical power using the results of a model of distribution of radiation in depth for different optical properties. The system was tested in tissue phantoms which allow a more controlled environment than test in vivo or in vitro.",

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Hernández-Quintanar, L , Stolik, S & De La Rosa, JM 2012, 'Experimental tests in tissue phantoms of a photoirradiation system with optical dosimetry for photodynamic therapy', Paper presented at 22nd Annual International Conference on Electronics, Communications and Computers, CONIELECOMP 2012, Cholula, Mexico, 27/02/12 - 29/02/12 pp. 45-49. https://doi.org/10.1109/CONIELECOMP.2012.6189879

Experimental tests in tissue phantoms of a photoirradiation system with optical dosimetry for photodynamic therapy. / Hernández-Quintanar, L.; Stolik, S.; De La Rosa, J. M.
2012. 45-49 Paper presented at 22nd Annual International Conference on Electronics, Communications and Computers, CONIELECOMP 2012, Cholula, Mexico.

Research output: Contribution to conference › Paper › peer-review

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AU - Stolik, S.

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AB - Photodynamic therapy involves the administration of a photosensitizer drug followed by a local illumination with light of specific wavelength. In the presence of oxygen molecules, the light illumination of photosensitizer can activate the production of reactive oxygen species which produce the death of malignant cells. Light dose is an important factor for reach an effective therapy. In this work it is presented an irradiation system which allows the application of radiation at 630 nm for 5-AminoLevulinic Acid superficial Photodynamic Therapy using as a light source, a light emitting diode and an automatic control of output optical power using the results of a model of distribution of radiation in depth for different optical properties. The system was tested in tissue phantoms which allow a more controlled environment than test in vivo or in vitro.

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DO - 10.1109/CONIELECOMP.2012.6189879

M3 - Artículo

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T2 - 22nd Annual International Conference on Electronics, Communications and Computers, CONIELECOMP 2012

Y2 - 27 February 2012 through 29 February 2012

ER -

Experimental tests in tissue phantoms of a photoirradiation system with optical dosimetry for photodynamic therapy

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