(−)-Epicatechin modifies body composition of the male offspring of obese rats

Sergio de los Santos, Ramón Mauricio Coral-Vázquez, Marta Menjivar, María de los Ángeles Granados-Silvestre, María Elena Tejeda, Luis Antonio Reyes-Castro, Juan Pablo Méndez, Elena Zambrano, Patricia Canto

Research output: Contribution to journalArticle

Abstract

The aim of our study was to determine if two protocols of (−)-epicatechin (Epi) (short and long) can modify fat, muscle and bone mass, in the male offspring of the maternal rat obesity model induced by high-fat diet (HFD). Four male offspring per group from different litters were randomly selected to the control or Epi intervention groups. We administered Epi twice daily/13 weeks (long) or for two weeks (short). The long Epi administration induced a significant decrease in the amount of total and visceral fat and an increased lean mass. Besides, short Epi administration increased whole body BMD of the male offspring of the control and maternal obesity groups. In conclusion, the administration of long Epi protocol elicited better results in decreasing total fat and all fat deposits and increased lean mass. However, only the short Epi protocol increased the total BMD in the male offspring.

Original languageEnglish
Pages (from-to)367-373
Number of pages7
JournalJournal of Functional Foods
Volume58
DOIs
StatePublished - Jul 2019

Fingerprint

Catechin
epicatechin
Body Composition
body composition
rats
Fats
obesity
lipids
Obesity
Mothers
visceral fat
Intra-Abdominal Fat
High Fat Diet
high fat diet
bones
Bone and Bones
Muscles
muscles

Keywords

  • (−)-Epicatechin
  • Bone density
  • Fat mass
  • Male offspring
  • Muscle mass

Cite this

de los Santos, S., Coral-Vázquez, R. M., Menjivar, M., Granados-Silvestre, M. D. L. Á., Tejeda, M. E., Reyes-Castro, L. A., ... Canto, P. (2019). (−)-Epicatechin modifies body composition of the male offspring of obese rats. Journal of Functional Foods, 58, 367-373. https://doi.org/10.1016/j.jff.2019.05.014
de los Santos, Sergio ; Coral-Vázquez, Ramón Mauricio ; Menjivar, Marta ; Granados-Silvestre, María de los Ángeles ; Tejeda, María Elena ; Reyes-Castro, Luis Antonio ; Méndez, Juan Pablo ; Zambrano, Elena ; Canto, Patricia. / (−)-Epicatechin modifies body composition of the male offspring of obese rats. In: Journal of Functional Foods. 2019 ; Vol. 58. pp. 367-373.
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abstract = "The aim of our study was to determine if two protocols of (−)-epicatechin (Epi) (short and long) can modify fat, muscle and bone mass, in the male offspring of the maternal rat obesity model induced by high-fat diet (HFD). Four male offspring per group from different litters were randomly selected to the control or Epi intervention groups. We administered Epi twice daily/13 weeks (long) or for two weeks (short). The long Epi administration induced a significant decrease in the amount of total and visceral fat and an increased lean mass. Besides, short Epi administration increased whole body BMD of the male offspring of the control and maternal obesity groups. In conclusion, the administration of long Epi protocol elicited better results in decreasing total fat and all fat deposits and increased lean mass. However, only the short Epi protocol increased the total BMD in the male offspring.",
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de los Santos, S, Coral-Vázquez, RM, Menjivar, M, Granados-Silvestre, MDLÁ, Tejeda, ME, Reyes-Castro, LA, Méndez, JP, Zambrano, E & Canto, P 2019, '(−)-Epicatechin modifies body composition of the male offspring of obese rats', Journal of Functional Foods, vol. 58, pp. 367-373. https://doi.org/10.1016/j.jff.2019.05.014

(−)-Epicatechin modifies body composition of the male offspring of obese rats. / de los Santos, Sergio; Coral-Vázquez, Ramón Mauricio; Menjivar, Marta; Granados-Silvestre, María de los Ángeles; Tejeda, María Elena; Reyes-Castro, Luis Antonio; Méndez, Juan Pablo; Zambrano, Elena; Canto, Patricia.

In: Journal of Functional Foods, Vol. 58, 07.2019, p. 367-373.

Research output: Contribution to journalArticle

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AU - de los Santos, Sergio

AU - Coral-Vázquez, Ramón Mauricio

AU - Menjivar, Marta

AU - Granados-Silvestre, María de los Ángeles

AU - Tejeda, María Elena

AU - Reyes-Castro, Luis Antonio

AU - Méndez, Juan Pablo

AU - Zambrano, Elena

AU - Canto, Patricia

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de los Santos S, Coral-Vázquez RM, Menjivar M, Granados-Silvestre MDLÁ, Tejeda ME, Reyes-Castro LA et al. (−)-Epicatechin modifies body composition of the male offspring of obese rats. Journal of Functional Foods. 2019 Jul;58:367-373. https://doi.org/10.1016/j.jff.2019.05.014