El factor de crecimiento transformante-alpha (TGF-alpha) y el factor de crecimiento epidermoide (EGF) en el síndrome de ovarios poliquísticos: posible papel en la disminución de los mecanismos apoptóticos en el folículo.

Translated title of the contribution: Transforming growth factor alpha (TGF-alpha) and epidermoid growth factor (EGF) in polycystic ovary syndrome: potential role in the decrease of apoptosis mechanisms in the follicle

J. A. Morales González, J. Gutiérrez Salinas, J. Paz Avila, L. F. Sauceda González, J. L. Montes Balderas

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Knowledgement on ovary function regulation is advancing. Classic concept about endocrine regulation by sexual hormones and gonadotrophin has turning to an hypothesis: autocrine and paracrine factors as intra-ovarian regulators. Follicular growth and steroidogenesis are mainly driven by follicle stimulating hormone (FSH), luteine hormone (LH) and steroids. On the other hand, the presence of intra-ovarian growth factors have an important role in modulation of gonadotrophin effects on ovarian functions. The influence of this factors on follicle growth are described.

Translated title of the contributionTransforming growth factor alpha (TGF-alpha) and epidermoid growth factor (EGF) in polycystic ovary syndrome: potential role in the decrease of apoptosis mechanisms in the follicle
Original languageSpanish
Pages (from-to)218-226
Number of pages9
JournalGinecologia y Obstetricia de Mexico
Volume69
StatePublished - Jun 2001
Externally publishedYes

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