TY - JOUR
T1 - Effect of crude extracts of Erythrina americana Mill. on aggressive behavior in rats
AU - Garín-Aguilar, Ma Eugenia
AU - Ramírez Luna, Jorge E.
AU - Soto-Hernández, Marcos
AU - Valencia del Toro, Gustavo
AU - Martínez Vázquez, Mariano
PY - 2000/2
Y1 - 2000/2
N2 - Three alkaloid fractions were obtained from seeds of Erythrina americana: free alkaloids in hexane, free alkaloids in methanol and liberated alkaloids. The pharmacological evaluation of these fractions on rats showed that, administered in a dose of 3 mg/kg, the three fractions diminished the aggressive behavior. This is comparable when diazepam is used as a control. An interaction between the cholinergic and GABAergic system could be suggested. Copyright (C) 2000 Elsevier Science Ireland Ltd.
AB - Three alkaloid fractions were obtained from seeds of Erythrina americana: free alkaloids in hexane, free alkaloids in methanol and liberated alkaloids. The pharmacological evaluation of these fractions on rats showed that, administered in a dose of 3 mg/kg, the three fractions diminished the aggressive behavior. This is comparable when diazepam is used as a control. An interaction between the cholinergic and GABAergic system could be suggested. Copyright (C) 2000 Elsevier Science Ireland Ltd.
KW - Aggression
KW - Alkaloids
KW - Erythrina americana
KW - Pharmacology
UR - http://www.scopus.com/inward/record.url?scp=0034142384&partnerID=8YFLogxK
U2 - 10.1016/S0378-8741(99)00121-X
DO - 10.1016/S0378-8741(99)00121-X
M3 - Artículo
SN - 0378-8741
VL - 69
SP - 189
EP - 196
JO - Journal of Ethnopharmacology
JF - Journal of Ethnopharmacology
IS - 2
ER -