Effect of aqueous extract of Brickellia veronicaefolia on the gastrointestinal tract of guinea-pig, rats and mice

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Abstract

The aqueous extract of Brickellia veronicaefolia inhibited gastric emptying time in rats and intestinal motility in mice, both effects were manifested in a dose-related fashion. The crude extract inhibited the contractions induced by acetylcholine and histamine concentration-dependently in the guinea-pig ileum. In the castor oil diarrhoea test, the extract showed 90% protection from diarrhoea at 150 mg/kg.

Original languageEnglish
Pages (from-to)677-679
Number of pages3
JournalPhytotherapy Research
Volume10
Issue number8
DOIs
StatePublished - Dec 1996

Keywords

  • Brickellia veronicaefolia
  • antidiarrhoeal activity

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