Design and synthesis of three naphtol derivatives using the three component system

Three naphtol derivativesweresynthesized using several strategies; in first stage, was synthetized the compound 4(1-[(2-Amino-ethylamino)-phenyl-methyl]- naphthalen-2-ol) using the three-component system (β-naphtol, benzaldehyde and ethylenediamine).The secondstage involves the synthesis of1-{[2-Hex-1-ynyl- phenyl-amino)-ethylamino]-phenyl-methyl}-naphtalen-2-ol (6) by the reaction of 4 with 1-hexyne and benzaldheydeusing cupric chloride as catalyst. The third stage, was achieved by synthesis of 3,8-di(naphtyl-2-ol)-1,10-diphenyl-4,7- diaza-deca-1,9-diene (8) using the three-component system (cinamaldehyde, β-naphtol and ethylenediamine). The structure of all compounds obtainedwas confirmed by spectroscopy and spectrometry data. In conclusion, in this study we report some efficient methods for synthesis of naphtol derivatives. It is important to mention that the methods used are highly versatile and the yield is good.