TY - JOUR
T1 - Covid-19
T2 - Enfoque básico para entender sus tratamientos
AU - Cedillo-Alvarez, Carla
AU - Gallardo-Ortiz, Itzell A.
AU - López, Luis T.
AU - Montes, Sergio
AU - Páez-Martínez, Nayeli
N1 - Publisher Copyright:
© 2019 Academia Nacional de Medicina de México, A.C.
PY - 2020
Y1 - 2020
N2 - SARS-CoV-2 virus has been identified as the causative agent of the COVID-19 pandemic. Even when no standard treatment is available, antivirals such as remdesivir and other drugs such as chloroquine and ivermectin, which interfere with viral repli-cation, have been assayed. Some strategies aimed to reduce immune mechanisms, such as the use of tocilizumab and natural antioxidants, have also been tested. The use of drugs related to the renin-angiotensin system has been controversial. Pathogenicity mechanisms, as well as controlled treatments, still have to be studied in detail in order to propose a viable therapeutic option that prevents the entry and replication of the virus or enhances the host immune system.
AB - SARS-CoV-2 virus has been identified as the causative agent of the COVID-19 pandemic. Even when no standard treatment is available, antivirals such as remdesivir and other drugs such as chloroquine and ivermectin, which interfere with viral repli-cation, have been assayed. Some strategies aimed to reduce immune mechanisms, such as the use of tocilizumab and natural antioxidants, have also been tested. The use of drugs related to the renin-angiotensin system has been controversial. Pathogenicity mechanisms, as well as controlled treatments, still have to be studied in detail in order to propose a viable therapeutic option that prevents the entry and replication of the virus or enhances the host immune system.
KW - Covid-19
KW - Pharmacological treatments
KW - Renin-angiotensin system
UR - http://www.scopus.com/inward/record.url?scp=85102856086&partnerID=8YFLogxK
U2 - 10.24875/GMM.20000452
DO - 10.24875/GMM.20000452
M3 - Artículo de revisión
C2 - 33877122
AN - SCOPUS:85102856086
SN - 0016-3813
VL - 156
SP - 580
EP - 585
JO - Gaceta Medica de Mexico
JF - Gaceta Medica de Mexico
IS - 6
ER -