TY - JOUR
T1 - Correlation between the concentration of DNA and electrical bioimpedance
AU - Hernández, Angélica
AU - Ames, Gerardo
AU - Sánchez, Virginia
AU - Gómez, Modesto
AU - Sánchez, Jennifer
AU - Pérez, Nadia M.
AU - Castillo, Itsi A.
AU - González, César A.
N1 - Publisher Copyright:
© Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence.
PY - 2021/11/15
Y1 - 2021/11/15
N2 - Biosensors have recently been used for the identification and genetic characterization of diseases such as Salmonella, human papilloma, and breast cancer. The aim of this study was to examine the relationship between different concentrations of Deoxyribonucleic Acid (DNA) and the corresponding values of magnitude and phase of Electrical Bioimpedance (EBI). Functions that characterize the correlation of DNA with these two parameters were derived from linear regression by means of the least squares method. According to the results, it is feasible to determine the concentration of DNA from EBI measurements (at a specific frequency) of magnitude and phase, taking into account the corresponding linear functions. The present findings indicate the feasibility of using EBI measurements of magnitude and phase as a biosensor for the detection of genes associated with genetic and infectious diseases.
AB - Biosensors have recently been used for the identification and genetic characterization of diseases such as Salmonella, human papilloma, and breast cancer. The aim of this study was to examine the relationship between different concentrations of Deoxyribonucleic Acid (DNA) and the corresponding values of magnitude and phase of Electrical Bioimpedance (EBI). Functions that characterize the correlation of DNA with these two parameters were derived from linear regression by means of the least squares method. According to the results, it is feasible to determine the concentration of DNA from EBI measurements (at a specific frequency) of magnitude and phase, taking into account the corresponding linear functions. The present findings indicate the feasibility of using EBI measurements of magnitude and phase as a biosensor for the detection of genes associated with genetic and infectious diseases.
UR - http://www.scopus.com/inward/record.url?scp=85120779516&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/2008/1/012021
DO - 10.1088/1742-6596/2008/1/012021
M3 - Artículo de la conferencia
AN - SCOPUS:85120779516
SN - 1742-6588
VL - 2008
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012021
T2 - 4th Latin American Conference on Bioimpedance 2021, CLABIO 2021
Y2 - 10 November 2021 through 13 November 2021
ER -
