Cocoa seed proteins' (theobroma cacao l.) anti-obesity potential through lipase inhibition using in silico, in vitro and in vivo models

Medicine & Life Sciences

• Cacao 100%
• Lipase 64%
• Seeds 59%
• High Fat Diet 58%
• Computer Simulation 55%
• Orlistat 42%
• Obesity 40%
• plant vicilin protein 28%
• In Vitro Techniques 25%
• Protein Hydrolysates 21%
• Proteins 21%
• Diet 20%
• Peptides 18%
• Noncommunicable Diseases 17%
• Intestinal Absorption 16%
• Feces 14%
• Hydrolysis 13%
• Inhibitory Concentration 50 13%
• Albumins 12%
• Triglycerides 11%
• Fats 11%
• Lipids 9%
• Enzymes 8%

Agriculture & Biology

• Theobroma cacao 75%
• triacylglycerol lipase 73%
• high fat diet 63%
• obesity 61%
• seeds 30%
• excretion 23%
• intragastric administration 22%
• vicilin 21%
• noninfectious diseases 21%
• peptides 20%
• proteins 19%
• intestinal absorption 18%
• hepatotoxicity 17%
• protein hydrolysates 17%
• lipids 15%
• diet 15%
• hydrolysates 14%
• albumins 13%
• animal models 12%
• inhibitory concentration 50 12%
• feces 11%
• triacylglycerols 11%
• hydrolysis 10%
• toxicity 10%
• prediction 9%
• enzyme activity 9%
• metabolism 8%
• rats 7%

Social Sciences

• Group 8%