TY - JOUR
T1 - Chromium toxic effect monitoring using ozonation method
AU - Poznyak, T.
AU - Puga, J. M.
AU - Kiseleva, E.
AU - Martinez, L.
PY - 2002
Y1 - 2002
N2 - The hexavalent chromium toxicity (in vitro) to plasma, erythrocytes, and semen lipids was evaluated. The ozonation technique is suggested to realize the rapid measurements of the lipid peroxidation (LPO) by means of the double bond indexes (DB-index and DBcell-index) calculation. The obtained experimental results permit to conclude that it is possible to detect the chromium effect on LPO by ozonation. The DB-index and DBcell-index determination in the plasma, erythrocytes, and sperm can be considered as a measure of this effect. Ozonation, suggested in this work, can provide the useful preliminary information for specialists and is a quantitative, fast, inexpensive, and simple method. In view of these comments, we conclude that the suggested ozonation method can be considered as the acceptable modern technique for the chromium toxic effect monitoring in vitro.
AB - The hexavalent chromium toxicity (in vitro) to plasma, erythrocytes, and semen lipids was evaluated. The ozonation technique is suggested to realize the rapid measurements of the lipid peroxidation (LPO) by means of the double bond indexes (DB-index and DBcell-index) calculation. The obtained experimental results permit to conclude that it is possible to detect the chromium effect on LPO by ozonation. The DB-index and DBcell-index determination in the plasma, erythrocytes, and sperm can be considered as a measure of this effect. Ozonation, suggested in this work, can provide the useful preliminary information for specialists and is a quantitative, fast, inexpensive, and simple method. In view of these comments, we conclude that the suggested ozonation method can be considered as the acceptable modern technique for the chromium toxic effect monitoring in vitro.
KW - Chromium Effect
KW - Erythrocytes
KW - Ozonation
KW - Plasma
KW - Semen
UR - http://www.scopus.com/inward/record.url?scp=0035987899&partnerID=8YFLogxK
U2 - 10.1080/10915810290096342
DO - 10.1080/10915810290096342
M3 - Artículo
SN - 1091-5818
VL - 21
SP - 211
EP - 217
JO - International Journal of Toxicology
JF - International Journal of Toxicology
IS - 3
ER -