C-26 and C-30 apocarotenoids from seeds of Ditaxis heterantha with antioxidant activity and protection against DNA oxidative damage

María D. Méndez-Robles, Herry H. Permady, María E. Jaramillo-Flores, Eugenia C. Lugo-Cervantes, Anaberta Cardador-Martínez, Alejandro A. Canales-Aguirre, Fernando López-Dellamary, Carlos M. Cerda-García-Rojas, Joaquín Tamariz

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The hexane extracts of seeds of Ditaxis heterantha afforded two new apocarotenoids whose structures corresponded to methyl 3-oxo-12′-apo- ε-caroten-12′-oate (1) (heteranthin) and methyl 3β,6β- epoxy-5β-hydroxy-4,5-dihydro-8′-apo-ε-caroten-8′-oate (2) (ditaxin). Both compounds were evaluated for antioxidant activity and protection against DNA oxidative damage by using DPPH. free radical scavenging and Comet assays, respectively.

Original languageEnglish
Pages (from-to)1140-1144
Number of pages5
JournalJournal of Natural Products
Volume69
Issue number8
DOIs
StatePublished - Aug 2006

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