TY - JOUR
T1 - Biological activities from the marine sponge suberites aurantiacus
AU - García-Davis, Sara
AU - Muñoz-Ochoa, Mauricio
AU - Rivas-Morales, Catalina
AU - Viveros-Valdez, Ezequiel
N1 - Publisher Copyright:
© 2018 Sara García-Davis et al.
PY - 2018
Y1 - 2018
N2 - Background and Objective: Invertebrates comprises more than fifty percent of marine animals. Among them, sponges are the most prolific source of bioactive compounds. Suberites aurantiacus (S. aurantiacus) is an abundant sponge in Mexican Pacific, which has been scarcely studied, for this reason authors screened it for its bioactivities. The current study proposed to determine the enzymatic inhibition and scavenger, toxic and antibacterial activities from Suberites aurantiacus. Materials and Methods: S. aurantiacus samples were collected in Magdalena Bay, Mexico. The ethanolic extract and its fractions were assayed for their antioxidant effect using DPPH, ABTS and NO assays, evaluated their toxicity against Artemia salina (A salina) and their antibacterial activity against Staphylococcusaureus(S. aureus), Bacillussubtilis(B. subtiiis), Enterococcus faecaiis{£ faecalis), Enterobacter aerogenes(E. aerogenes), Escherichia coil(E coil) and Klebsiella pneumoniae (K. pneumoniae) as well as their inhibitory effect on α-glucosidase and α-amylase. Results: The results showed median lethal doses (LD50) against A. salina < 1 mg mL-1 for two fractions and a moderate antibacterial activity againstGram positive bacteria. Conclusion: In view of these results, S. aurantiacus could be considered a potential source of antibacterial compounds.
AB - Background and Objective: Invertebrates comprises more than fifty percent of marine animals. Among them, sponges are the most prolific source of bioactive compounds. Suberites aurantiacus (S. aurantiacus) is an abundant sponge in Mexican Pacific, which has been scarcely studied, for this reason authors screened it for its bioactivities. The current study proposed to determine the enzymatic inhibition and scavenger, toxic and antibacterial activities from Suberites aurantiacus. Materials and Methods: S. aurantiacus samples were collected in Magdalena Bay, Mexico. The ethanolic extract and its fractions were assayed for their antioxidant effect using DPPH, ABTS and NO assays, evaluated their toxicity against Artemia salina (A salina) and their antibacterial activity against Staphylococcusaureus(S. aureus), Bacillussubtilis(B. subtiiis), Enterococcus faecaiis{£ faecalis), Enterobacter aerogenes(E. aerogenes), Escherichia coil(E coil) and Klebsiella pneumoniae (K. pneumoniae) as well as their inhibitory effect on α-glucosidase and α-amylase. Results: The results showed median lethal doses (LD50) against A. salina < 1 mg mL-1 for two fractions and a moderate antibacterial activity againstGram positive bacteria. Conclusion: In view of these results, S. aurantiacus could be considered a potential source of antibacterial compounds.
KW - Antioxidant enzyme inhibition
KW - Bactericide
KW - Sponge
KW - Toxicity
UR - http://www.scopus.com/inward/record.url?scp=85046115988&partnerID=8YFLogxK
U2 - 10.3923/jbs.2018.152.157
DO - 10.3923/jbs.2018.152.157
M3 - Artículo
AN - SCOPUS:85046115988
SN - 1727-3048
VL - 18
SP - 152
EP - 157
JO - Journal of Biological Sciences
JF - Journal of Biological Sciences
IS - 3
ER -