Bioavailability of praziquantel increases with concomitant administration of food

N. Castro; R. Medina; J. Sotelo; H. Jung

doi:10.1128/AAC.44.10.2903-2904.2000

Bioavailability of praziquantel increases with concomitant administration of food

N. Castro, R. Medina, J. Sotelo, H. Jung

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.

Original language	English
Pages (from-to)	2903-2904
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	44
Issue number	10
DOIs	https://doi.org/10.1128/AAC.44.10.2903-2904.2000
State	Published - 2000
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1128/AAC.44.10.2903-2904.2000

Cite this

@article{08f736e3c81842108af7892e5b0b2ec2,

title = "Bioavailability of praziquantel increases with concomitant administration of food",

abstract = "In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.",

author = "N. Castro and R. Medina and J. Sotelo and H. Jung",

year = "2000",

doi = "10.1128/AAC.44.10.2903-2904.2000",

language = "Ingl{\'e}s",

volume = "44",

pages = "2903--2904",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

number = "10",

}

TY - JOUR

T1 - Bioavailability of praziquantel increases with concomitant administration of food

AU - Castro, N.

AU - Medina, R.

AU - Sotelo, J.

AU - Jung, H.

PY - 2000

Y1 - 2000

N2 - In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.

AB - In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.

UR - http://www.scopus.com/inward/record.url?scp=0033802585&partnerID=8YFLogxK

U2 - 10.1128/AAC.44.10.2903-2904.2000

DO - 10.1128/AAC.44.10.2903-2904.2000

M3 - Artículo

C2 - 10991886

AN - SCOPUS:0033802585

SN - 0066-4804

VL - 44

SP - 2903

EP - 2904

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 10

ER -

Bioavailability of praziquantel increases with concomitant administration of food

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this