Abstract
The tuberculosis has increased by the emergence of multidrug-resistant strain (MDR). Was associated clinical course of patients with tuberculosis and treatment resistance. 268 samples were obtained, the resistance to drugs was determined for blue Alamar; 41.04% corresponded to strain sensitive to all the drugs; 17.91% MDR. The resistance was: isoniazid 28%, rifampin 52%, streptomycin 24%, and ethambutol 27%. Of 268 patients, 197 were virgins to treatment, of which 44% presented primary resistance, but of these, only 5% MDR. 71 patients (26.49%) with previous treatment presented secondary resistance, of which 14.55% was MDR. At the end of the follow-up, 72% recovered, 21% remained sick, and 7% died. The patients with better forecast were with sensitive strain, followed by patients with primary resistance and those of badly forecast they were MDR.
Translated title of the contribution | Association between the clinical course of patients with tuberculosis and the treatment resistance of isolates of Mycobacterium |
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Original language | English |
Pages (from-to) | 64-71 |
Number of pages | 8 |
Journal | Revista Mexicana de Ciencias Farmaceuticas |
Volume | 43 |
Issue number | 1 |
State | Published - 2012 |
Externally published | Yes |
Keywords
- Isoniazid
- Resistance
- Rifampin