Antioxidant activity of a new multiflorane-type triterpene from Cucurbita argyrosperma seeds and their protective role in hydrogen peroxide induced oxidative stress

Agriculture & Biology

• Cucurbita argyrosperma 100%
• triterpenoids 54%
• hydrogen peroxide 46%
• oxidative stress 41%
• antioxidant activity 38%
• seeds 27%
• cells 16%
• caspase-3 9%
• antioxidants 7%
• oxidants 7%
• cell viability 7%
• apoptosis 6%
• antioxidant enzymes 6%
• cytotoxicity 6%
• pretreatment 5%
• noninsulin-dependent diabetes mellitus 4%
• sulfonic acids 4%
• plant diseases and disorders 4%
• lactate dehydrogenase 3%
• protective effect 3%
• glutathione peroxidase 3%
• chemical structure 3%
• cell death 3%
• glutathione 3%
• reactive oxygen species 3%
• lipid peroxidation 3%
• catalase 3%
• superoxide dismutase 2%
• cell lines 2%
• pathogens 2%
• assays 2%
• extracts 1%
• rats 1%
• enzymes 1%
• methodology 1%

Medicine & Life Sciences

• Cucurbita 79%
• Triterpenes 66%
• Seeds 54%
• Hydrogen Peroxide 53%
• Antioxidants 39%
• Oxidative Stress 38%
• Oxidants 7%
• Caspase 3 6%
• Enzymes 6%
• Plant Diseases 6%
• Adenosine Triphosphate 5%
• Cell Survival 5%
• 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid 5%
• Sulfonic Acids 4%
• Apoptosis 4%
• Glutathione Peroxidase 3%
• L-Lactate Dehydrogenase 3%
• Catalase 3%
• Free Radicals 3%
• Lipid Peroxidation 3%
• Superoxide Dismutase 3%
• Glutathione 3%
• Reactive Oxygen Species 3%
• Cell Death 2%
• Type 2 Diabetes Mellitus 2%
• Anti-Inflammatory Agents 2%
• Cell Line 2%

Chemistry

• Triterpene 60%
• Oxidative Stress 52%
• Protective 43%
• Hydrogen Peroxide 40%
• Antioxidant Agent 40%
• Cell Viability 17%
• Glutathione 15%
• Cell Death 9%
• Lactate 8%
• Superoxide 8%
• Antiinflammatory 8%
• Reactive Oxygen Metabolite 8%
• Peroxidase 7%
• Occurrence in Nature 7%
• Lipid 6%
• Acid 3%